N-Nitroso Valsartan Methyl Ester

Name: N-Nitroso Valsartan Methyl Ester
Brand: Vaqora Chemicals
SKU: VQ-006965

About N-Nitroso Valsartan Methyl Ester

N-Nitroso Valsartan Methyl Ester is a nitrosamine impurity of Valsartan carrying the CAS registry number 2851532-34-6. With the molecular formula C20H22N6O3, it has a molar mass of 394.4 g/mol. Systematically, it is named methyl (2R)-3-methyl-2-[nitroso-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Valsartan, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso Valsartan Methyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Valsartan Methyl Ester
Catalogue No.	VQ-006965
CAS Number	2851532-34-6
IUPAC name	methyl (2R)-3-methyl-2-[nitroso-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate
Molecular formula	C₂₀H₂₂N₆O₃
Molecular weight	394.4 g/mol
Exact mass	394.1753
Grade	Reference Standard
HSN code	38229090
InChIKey	JBFJLETZIOUPNG-GOSISDBHSA-N
SMILES	CC(C)[C@H](C(=O)OC)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)N=O
PubChem CID	178247671

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 8
TPSA	113 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Valsartan Methyl Ester?

The CAS Registry Number of N-Nitroso Valsartan Methyl Ester is 2851532-34-6. It is also known as methyl N-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-nitroso-D-valinate.

What is the molecular formula and molecular weight of N-Nitroso Valsartan Methyl Ester?

N-Nitroso Valsartan Methyl Ester has the molecular formula C20H22N6O3 and a molecular weight of 394.4 g/mol. Its IUPAC name is methyl (2R)-3-methyl-2-[nitroso-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate.

What is N-Nitroso Valsartan Methyl Ester used for?

N-Nitroso Valsartan Methyl Ester is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Valsartan Methyl Ester can I order?

We supply N-Nitroso Valsartan Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Valsartan Methyl Ester?

Yes. Every lot of N-Nitroso Valsartan Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Valsartan Methyl Ester be shipped internationally?

Yes. We export N-Nitroso Valsartan Methyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.