Valsartan Impurity 8 (Hydrochloride)

Name: Valsartan Impurity 8 (Hydrochloride)
Brand: Vaqora Chemicals
SKU: VQ-006099

About Valsartan Impurity 8 (Hydrochloride)

Vaqora Chemicals supplies Valsartan Impurity 8 (Hydrochloride), an impurity of Valsartan registered under CAS number 482577-59-3. Formula C20H23ClN2O2, molecular weight 358.9 g/mol. Its systematic (IUPAC) name is methyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-methylbutanoate. Hydrochloride. It is also known as Valsartan Cyano Desvaleryl Methyl Ester or Valsartan Impurity 56 HCl.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

This Valsartan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Valsartan Impurity 8 (Hydrochloride) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Valsartan Impurity 8 (Hydrochloride)
Catalogue No.	VQ-006099
CAS Number	482577-59-3
Other CAS	137863-89-9
IUPAC name	methyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-methylbutanoate;hydrochloride
Molecular formula	C₂₀H₂₃ClN₂O₂
Molecular weight	358.9 g/mol
Exact mass	358.1448
Grade	Reference Standard
HSN code	38229090
InChIKey	AZQXUWUZQLZNIM-FYZYNONXSA-N
SMILES	CC(C)[C@@H](C(=O)OC)NCC1=CC=C(C=C1)C2=CC=CC=C2C#N.Cl
PubChem CID	16744793

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	62.1 Å²
Synonyms	Methyl ((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valinate Hydrochloride, Valsartan Cyano Desvaleryl Methyl Ester, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride, N-(2'-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester hydrochloride (1:1), N-(2-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride, N-[(2'-cyanobiphenyl-4-yl)methyl]-(L)-valine methyl ester hydrochloride, (S)-Methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoate HCl, Valsartan Impurity 56 HCl, N-(2'-Cyanobiphenyl-4-ylMethyl)-L-valine Methyl Ester HCl, N-[(2'-cyanobiphenyl-4-yl) methyl]-(L)-valine methyl ester hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Valsartan Impurity 8 (Hydrochloride)?

The CAS Registry Number of Valsartan Impurity 8 (Hydrochloride) is 482577-59-3. It is also known as Methyl ((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valinate Hydrochloride, Valsartan Cyano Desvaleryl Methyl Ester, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride.

What is the molecular formula and molecular weight of Valsartan Impurity 8 (Hydrochloride)?

Valsartan Impurity 8 (Hydrochloride) has the molecular formula C20H23ClN2O2 and a molecular weight of 358.9 g/mol.

What is Valsartan Impurity 8 (Hydrochloride) used for?

Valsartan Impurity 8 (Hydrochloride) is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Valsartan Impurity 8 (Hydrochloride) can I order?

We supply Valsartan Impurity 8 (Hydrochloride) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Valsartan Impurity 8 (Hydrochloride)?

Yes. Every lot of Valsartan Impurity 8 (Hydrochloride) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Valsartan Impurity 8 (Hydrochloride) be shipped internationally?

Yes. Valsartan Impurity 8 (Hydrochloride) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.