Naltrexone EP Impurity D

Name: Naltrexone EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-026821

About Naltrexone EP Impurity D

Naltrexone EP Impurity D is a pharmacopeial impurity of Naltrexone carrying the CAS registry number 607732-61-6. Formula C40H44N2O8, molecular weight 680.8 g/mol. Alternative names: Naltrexone Hydrochloride - Impurity D and 2,2'-Bisnaltrexone.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Naltrexone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Naltrexone EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Naltrexone EP Impurity D
Catalogue No.	VQ-026821
CAS Number	607732-61-6
IUPAC name	(4R,4aS,7aR,12bS)-10-[(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-10-yl]-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formula	C₄₀H₄₄N₂O₈
Molecular weight	680.8 g/mol
Exact mass	680.3098
Grade	Reference Standard
HSN code	38229090
InChIKey	NGSAYZAPVYNVHK-YAUKWVCOSA-N
SMILES	C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=CC(=C(C(=C46)O5)O)C7=C(C8=C9C(=C7)C[C@@H]1[C@]2([C@]9(CCN1CC1CC1)[C@@H](O8)C(=O)CC2)O)O)O
PubChem CID	90475041

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	4 / 10
TPSA	140 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naltrexone EP Impurity D?

The CAS Registry Number of Naltrexone EP Impurity D is 607732-61-6. It is also known as Naltrexone Hydrochloride - Impurity D, 2,2'-Bisnaltrexone.

What is the molecular formula and molecular weight of Naltrexone EP Impurity D?

Naltrexone EP Impurity D has the molecular formula C40H44N2O8 and a molecular weight of 680.8 g/mol.

What is Naltrexone EP Impurity D used for?

Naltrexone EP Impurity D is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naltrexone EP Impurity D can I order?

We supply Naltrexone EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naltrexone EP Impurity D?

Yes. Every lot of Naltrexone EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naltrexone EP Impurity D be shipped internationally?

Yes. Naltrexone EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.