Naproxen EP Impurity F

Name: Naproxen EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-006519

About Naproxen EP Impurity F

Listed under CAS 31220-35-6, Naproxen EP Impurity F is a pharmacopeial impurity of Naproxen available from Vaqora Chemicals at a purity of 96.9%. Its molecular formula is C16H18O3 and its molecular weight is 258.31 g/mol. Systematically, it is named ethyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate. Alternative names: (+)-(S)-Naproxen ethyl ester and (+)-Naproxen ethyl ester.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Naproxen, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Naproxen EP Impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Naproxen

View every impurity, metabolite and intermediate we list for Naproxen.

Naproxen impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Naproxen EP Impurity F
Catalogue No.	VQ-006519
CAS Number	31220-35-6
IUPAC name	ethyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
Molecular formula	C₁₆H₁₈O₃
Molecular weight	258.31 g/mol
Exact mass	258.1256
Grade	Reference Standard
Purity / assay	96.9%
HSN code	38229090
InChIKey	URNAYRDBUUZOIU-NSHDSACASA-N
SMILES	CCOC(=O)[C@@H](C)C1=CC2=C(C=C1)C=C(C=C2)OC
PubChem CID	711615

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²
Synonyms	(+)-(S)-Naproxen ethyl ester, (alphaS)-6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid Ethyl Ester, (S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid Ethyl Ester, (+)-Naproxen ethyl ester, (S)-Ethyl naproxen, Naproxen ethyl ester, (S)-Naproxen Ethyl Ester, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, ethyl ester, (alphaS)-, Naproxen impurity F, Naproxen sodium impurity F, (S)-Ethyl 2-(6-methoxynaphthalen-2-yl)propanoate, Ethyl (2S)-2-(6-Methoxynaphthalen-2-yl)propanoate (Naproxen Ethyl Ester)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naproxen EP Impurity F?

The CAS Registry Number of Naproxen EP Impurity F is 31220-35-6. It is also known as (+)-(S)-Naproxen ethyl ester, (alphaS)-6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid Ethyl Ester, (S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid Ethyl Ester.

What is the molecular formula and molecular weight of Naproxen EP Impurity F?

Naproxen EP Impurity F has the molecular formula C16H18O3 and a molecular weight of 258.31 g/mol. Its IUPAC name is ethyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate.

What is Naproxen EP Impurity F used for?

Naproxen EP Impurity F is supplied as a characterised reference material related to Naproxen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naproxen EP Impurity F can I order?

We supply Naproxen EP Impurity F in Reference Standard (96.9%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naproxen EP Impurity F?

Yes. Every lot of Naproxen EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naproxen EP Impurity F be shipped internationally?

Yes. Naproxen EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.