Neratinib WS

Name: Neratinib WS
Brand: Vaqora Chemicals
SKU: VQ-007609

About Neratinib WS

Neratinib WS is a high-purity reference standard of Neratinib carrying the CAS registry number 698387-09-6. Its molecular formula is C30H29ClN6O3 and its molecular weight is 557.0 g/mol. It is also known as Neratinib or HKI 272.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Neratinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Neratinib WS in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Neratinib

View every impurity, metabolite and intermediate we list for Neratinib.

Neratinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Neratinib WS
Catalogue No.	VQ-007609
CAS Number	698387-09-6
Other CAS	915942-22-2
IUPAC name	(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Molecular formula	C₃₀H₂₉ClN₆O₃
Molecular weight	557 g/mol
Exact mass	556.199
Grade	Reference Standard
HSN code	38229090
InChIKey	JWNPDZNEKVCWMY-VQHVLOKHSA-N
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C
PubChem CID	9915743

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	2 / 8
TPSA	112 Å²
Synonyms	Neratinib, HKI 272, HKI-272, PB-272, CDP-820, PB 272, Neratinib (HKI-272), C30H29ClN6O3, 698387-09-6 (free base), Neratinib (Standard), Neratinib (USAN/INN), Neratinib (HKI-272)?

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neratinib WS?

The CAS Registry Number of Neratinib WS is 698387-09-6. It is also known as Neratinib, HKI 272, HKI-272.

What is the molecular formula and molecular weight of Neratinib WS?

Neratinib WS has the molecular formula C30H29ClN6O3 and a molecular weight of 557 g/mol. Its IUPAC name is (E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide.

What is Neratinib WS used for?

Neratinib WS is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neratinib WS can I order?

We supply Neratinib WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neratinib WS?

Yes. Every lot of Neratinib WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neratinib WS be shipped internationally?

Yes. Neratinib WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.