Nicotine EP Impurity C

Name: Nicotine EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-032133

About Nicotine EP Impurity C

Vaqora Chemicals supplies Nicotine EP Impurity C, a pharmacopeial impurity of Nicotine Hemisulfate registered under CAS number 486-56-6. Formula C10H12N2O, molecular weight 176.21 g/mol. The IUPAC name is (5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one. It is also known as S-(-)-Cotinine or (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Nicotine Hemisulfate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nicotine Hemisulfate

View every impurity, metabolite and intermediate we list for Nicotine Hemisulfate.

Nicotine Hemisulfate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nicotine EP Impurity C
Catalogue No.	VQ-032133
CAS Number	486-56-6
IUPAC name	(5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one
Molecular formula	C₁₀H₁₂N₂O
Molecular weight	176.21 g/mol
Exact mass	176.095
Grade	Reference Standard
HSN code	38229090
InChIKey	UIKROCXWUNQSPJ-VIFPVBQESA-N
SMILES	CN1[C@@H](CCC1=O)C2=CN=CC=C2
PubChem CID	854019

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	0 / 2
TPSA	33.2 Å²
Synonyms	S-(-)-Cotinine, (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one, cotinine, (-)-Cotinine, (S)-(-)-Cotinine, (S)-Cotinine, (5S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one, (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone, 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5S)-, 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (S)-, n-methyl-2-(3-pyridyl)-5-pyrrolidone, Scotine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nicotine EP Impurity C?

The CAS Registry Number of Nicotine EP Impurity C is 486-56-6. It is also known as S-(-)-Cotinine, (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one, cotinine.

What is the molecular formula and molecular weight of Nicotine EP Impurity C?

Nicotine EP Impurity C has the molecular formula C10H12N2O and a molecular weight of 176.21 g/mol. Its IUPAC name is (5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one.

What is Nicotine EP Impurity C used for?

Nicotine EP Impurity C is supplied as a characterised reference material related to Nicotine Hemisulfate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nicotine EP Impurity C can I order?

We supply Nicotine EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nicotine EP Impurity C?

Yes. Every lot of Nicotine EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nicotine EP Impurity C be shipped internationally?

Yes. Nicotine EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.