Nifedipine EP Impurity A

Name: Nifedipine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-023250

About Nifedipine EP Impurity A

Vaqora Chemicals supplies Nifedipine EP Impurity A, a pharmacopeial impurity of Nifedipine registered under CAS number 67035-22-7. Formula C17H16N2O6, molecular weight 344.32 g/mol. The IUPAC name is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate. Alternative names: Dehydronifedipine and Nifedipine - Impurity A.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Nifedipine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nifedipine EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nifedipine

View every impurity, metabolite and intermediate we list for Nifedipine.

Nifedipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nifedipine EP Impurity A
Catalogue No.	VQ-023250
CAS Number	67035-22-7
IUPAC name	dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
Molecular formula	C₁₇H₁₆N₂O₆
Molecular weight	344.32 g/mol
Exact mass	344.1008
Grade	Reference Standard
HSN code	38229090
InChIKey	UMQHJQGNGLQJPF-UHFFFAOYSA-N
SMILES	CC1=C(C(=C(C(=N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
PubChem CID	128753

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 7
TPSA	111 Å²
Synonyms	Dehydronifedipine, Nifedipine - Impurity A, Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate, BAY-b 4759, 4-(2-Nitrophenyl)-3,5-bis(carboxymethyl)-2,6-dimethylpyridine, 2,6-Dimethyl-4-(ortho-nitrophenyl)-3,5-pyridinedicarboxylic aciddimenthyl ester, 4-(2'-Nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid dimethyl ester, Dehydro Nifedipine, 4-(2-Nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid dimethyl ester, Nifedipine M (dehydro), 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate, Nifedipine-1

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements: P264 + P265, P280, P305 + P354 + P338, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nifedipine EP Impurity A?

The CAS Registry Number of Nifedipine EP Impurity A is 67035-22-7. It is also known as Dehydronifedipine, Nifedipine - Impurity A, Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate.

What is the molecular formula and molecular weight of Nifedipine EP Impurity A?

Nifedipine EP Impurity A has the molecular formula C17H16N2O6 and a molecular weight of 344.32 g/mol. Its IUPAC name is dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate.

What is Nifedipine EP Impurity A used for?

Nifedipine EP Impurity A is supplied as a characterised reference material related to Nifedipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nifedipine EP Impurity A can I order?

We supply Nifedipine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nifedipine EP Impurity A?

Yes. Every lot of Nifedipine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nifedipine EP Impurity A be shipped internationally?

Yes. Nifedipine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.