Nitrilotriacetamide
Synonyms: 2,2',2''-Nitrilotris(acetamide) · Acetamide, 2,2',2''-nitrilotris- · 2,2',2''-Nitrilotris[acetamide] · ntam cpd
Nitrilotriacetamide (CAS 4862-18-4) – Allopurinol impurity standard. C6H12N4O3, MW 188.18. Request a quote: COA, bulk packs and worldwide export.
About Nitrilotriacetamide
Nitrilotriacetamide is an impurity of Allopurinol carrying the CAS registry number 4862-18-4. The compound has the formula C6H12N4O3, corresponding to a molecular weight of 188.18 g/mol. Systematically, it is named 2-[bis(2-amino-2-oxoethyl)amino]acetamide. Alternative names: 2,2',2''-Nitrilotris(acetamide) and Acetamide, 2,2',2''-nitrilotris-.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.
Pharmaceutical QC and development laboratories use this impurity standard of Allopurinol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nitrilotriacetamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Allopurinol.
Allopurinol impuritiesSpecifications & identifiers
| Product name | Nitrilotriacetamide |
|---|---|
| Catalogue No. | VQ-047365 |
| CAS Number | 4862-18-4 |
| IUPAC name | 2-[bis(2-amino-2-oxoethyl)amino]acetamide |
| Molecular formula | C6H12N4O3 |
| Molecular weight | 188.18 g/mol |
| Exact mass | 188.0909 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | CVTGEDNIBVTKBJ-UHFFFAOYSA-N |
| SMILES | C(C(=O)N)N(CC(=O)N)CC(=O)N |
| PubChem CID | 78580 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | -2.9 |
| H-bond donors / acceptors | 3 / 4 |
| TPSA | 133 Ų |
| Synonyms | 2,2',2''-Nitrilotris(acetamide), Acetamide, 2,2',2''-nitrilotris-, 2,2',2''-Nitrilotris[acetamide], ntam cpd, Nitrilotris(acetamide), 2,2',2''-nitrilotriacetamide, Nitrilotris[acetamide], 2,2',2''-Nitrilotrisacetamide, 2,2''-Nitrilotrisacetamide, 2,2',2"-Nitrilotriacetamide, Acetamide,2',2''-nitrilotris- |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H315Causes skin irritationH319Causes serious eye irritation
Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Nitrilotriacetamide?
The CAS Registry Number of Nitrilotriacetamide is 4862-18-4. It is also known as 2,2',2''-Nitrilotris(acetamide), Acetamide, 2,2',2''-nitrilotris-, 2,2',2''-Nitrilotris[acetamide].
What is the molecular formula and molecular weight of Nitrilotriacetamide?
Nitrilotriacetamide has the molecular formula C6H12N4O3 and a molecular weight of 188.18 g/mol. Its IUPAC name is 2-[bis(2-amino-2-oxoethyl)amino]acetamide.
What is Nitrilotriacetamide used for?
Nitrilotriacetamide is supplied as a characterised reference material related to Allopurinol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Nitrilotriacetamide can I order?
We supply Nitrilotriacetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Nitrilotriacetamide?
Yes. Every lot of Nitrilotriacetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Nitrilotriacetamide be shipped internationally?
Yes. Nitrilotriacetamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Nitrilotriacetamide
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