Worldwide shipping · 120+ destinationsCOA & GHS SDS with every lotMon–Sat, 09:30–18:30 IST
VAQORACHEMICALS
Nitrosamine ImpuritiesReference StandardAvailable on request

Nitrosobiotin

Synonyms: 1'-Nitroso Biotin · 1'-Nitrosobiotin · 5-[(3as,4s,6ar)-1-nitroso-2-oxohexahydro-1h-thieno[3,4-d]imidazol-4-yl]pentanoic acid · 5-((3aS,4S,6aR)-1-nitroso-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid

CAS No.56859-26-8
FormulaC10H15N3O4S
Mol. weight273.31
Catalogue No.VQ-024600
PurityReference Standard
HSN38229090

Nitrosobiotin (CAS 56859-26-8) – nitrosamine impurity reference standard. C10H15N3O4S, MW 273.31. From Vaqora Chemicals, with COA and worldwide delivery.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire
Enquire
Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About Nitrosobiotin

Nitrosobiotin is a nitrosamine impurity of Biotin carrying the CAS registry number 56859-26-8. With the molecular formula C10H15N3O4S, it has a molar mass of 273.31 g/mol. Its systematic (IUPAC) name is 5-[(3aR,6S,6aS)-3-nitroso-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid. Common synonyms include 1'-Nitroso Biotin and 1'-Nitrosobiotin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Biotin, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

  • Nitrosamine risk assessment
  • Trace LC-MS/MS quantitation
  • Method validation (AMV)
  • Regulatory submissions

Industries

Related to Biotin

View every impurity, metabolite and intermediate we list for Biotin.

Biotin impurities

Specifications & identifiers

Chemical identifiers
Product nameNitrosobiotin
Catalogue No.VQ-024600
CAS Number56859-26-8
IUPAC name5-[(3aR,6S,6aS)-3-nitroso-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid
Molecular formulaC10H15N3O4S
Molecular weight273.31 g/mol
Exact mass273.0783
GradeReference Standard
HSN code38229090
InChIKeyIFUXQNNMTPBRPW-ZKWXMUAHSA-N
SMILESC1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2N=O
PubChem CID191424
Physical properties
Physical formSolid
LogP (XLogP3)0.2
H-bond donors / acceptors2 / 6
TPSA124 Ų

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard

Signal word: Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Nitrosobiotin?

The CAS Registry Number of Nitrosobiotin is 56859-26-8. It is also known as 1'-Nitroso Biotin, 1'-Nitrosobiotin, 5-[(3as,4s,6ar)-1-nitroso-2-oxohexahydro-1h-thieno[3,4-d]imidazol-4-yl]pentanoic acid.

What is the molecular formula and molecular weight of Nitrosobiotin?

Nitrosobiotin has the molecular formula C10H15N3O4S and a molecular weight of 273.31 g/mol. Its IUPAC name is 5-[(3aR,6S,6aS)-3-nitroso-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid.

What is Nitrosobiotin used for?

Nitrosobiotin is supplied as a characterised reference material related to Biotin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nitrosobiotin can I order?

We supply Nitrosobiotin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nitrosobiotin?

Yes. Every lot of Nitrosobiotin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nitrosobiotin be shipped internationally?

Yes. Nitrosobiotin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about Nitrosobiotin

We reply within one business day with price, pack options, lead time and documentation.

By submitting you agree to our privacy policy. We never share your details.

Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
How ordering works

Related products

Reference Standard
Biotin EP Impurity A chemical structure
Biotin EP Impurity A
CAS
1163708-46-0
Formula
C18H28N4O4S2
MW
428.6 g/mol
VQ-021841
Reference Standard
Biotin Sulfone chemical structure
Biotin Sulfone
CAS
40720-05-6
Formula
C10H16N2O5S
MW
276.31 g/mol
VQ-021838
Reference Standard
3N-Benzyl Biotin chemical structure
3N-Benzyl Biotin
CAS
57229-92-2
Formula
C17H22N2O3S
MW
334.4 g/mol
VQ-021837

More in Nitrosamine Impurities →