O-6-Benzyl Guanine

Name: O-6-Benzyl Guanine
Brand: Vaqora Chemicals
SKU: VQ-030496

About O-6-Benzyl Guanine

Listed under CAS 19916-73-5, O-6-Benzyl Guanine is an impurity of Entecavir available from Vaqora Chemicals. The compound has the formula C12H11N5O, corresponding to a molecular weight of 241.25 g/mol. The IUPAC name is 6-phenylmethoxy-7H-purin-2-amine. Common synonyms include 6-O-Benzylguanine and 2-Amino-6-(benzyloxy)purine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Entecavir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, O-6-Benzyl Guanine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Entecavir

View every impurity, metabolite and intermediate we list for Entecavir.

Entecavir impurities

Specifications & identifiers

Chemical identifiers
Product name	O-6-Benzyl Guanine
Catalogue No.	VQ-030496
CAS Number	19916-73-5
IUPAC name	6-phenylmethoxy-7H-purin-2-amine
Molecular formula	C₁₂H₁₁N₅O
Molecular weight	241.25 g/mol
Exact mass	241.0964
Grade	Reference Standard
HSN code	38229090
InChIKey	KRWMERLEINMZFT-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N
PubChem CID	4578

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	2 / 5
TPSA	89.7 Å²
Synonyms	6-O-Benzylguanine, 2-Amino-6-(benzyloxy)purine, O(6)-Bgua, 2-Amino-6-(phenylmethoxy)-9H-purine, 6-(Phenylmethoxy)-9H-purin-2-amine, 6-(Benzyloxy)-7H-purin-2-amine, 6-(benzyloxy)-9H-purin-2-amine, 2-amino-6-benzyloxypurine, 6-Benzyloxyguanine, KRX-0402

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-6-Benzyl Guanine?

The CAS Registry Number of O-6-Benzyl Guanine is 19916-73-5. It is also known as 6-O-Benzylguanine, 2-Amino-6-(benzyloxy)purine, O(6)-Bgua.

What is the molecular formula and molecular weight of O-6-Benzyl Guanine?

O-6-Benzyl Guanine has the molecular formula C12H11N5O and a molecular weight of 241.25 g/mol. Its IUPAC name is 6-phenylmethoxy-7H-purin-2-amine.

What is O-6-Benzyl Guanine used for?

O-6-Benzyl Guanine is supplied as a characterised reference material related to Entecavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-6-Benzyl Guanine can I order?

We supply O-6-Benzyl Guanine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-6-Benzyl Guanine?

Yes. Every lot of O-6-Benzyl Guanine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-6-Benzyl Guanine be shipped internationally?

Yes. O-6-Benzyl Guanine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.