O-Demethyl Vandetanib

Name: O-Demethyl Vandetanib
Brand: Vaqora Chemicals
SKU: VQ-028632

About O-Demethyl Vandetanib

O-Demethyl Vandetanib is a metabolite or degradation product of Vandetanib carrying the CAS registry number 910298-60-1. The compound has the formula C21H22BrFN4O2, corresponding to a molecular weight of 461.3 g/mol. Its systematic (IUPAC) name is 4-(4-bromo-2-fluoroanilino)-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-6-ol. Alternative names: O-Desmethyl Vandetanib.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Vandetanib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer O-Demethyl Vandetanib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Vandetanib

View every impurity, metabolite and intermediate we list for Vandetanib.

Vandetanib impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Demethyl Vandetanib
Catalogue No.	VQ-028632
CAS Number	910298-60-1
IUPAC name	4-(4-bromo-2-fluoroanilino)-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-6-ol
Molecular formula	C₂₁H₂₂BrFN₄O₂
Molecular weight	461.3 g/mol
Exact mass	460.091
Grade	Reference Standard
HSN code	38229090
InChIKey	XFRILWHQVZXWIN-UHFFFAOYSA-N
SMILES	CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)O
PubChem CID	70909613

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	2 / 7
TPSA	70.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Demethyl Vandetanib?

The CAS Registry Number of O-Demethyl Vandetanib is 910298-60-1. It is also known as O-Desmethyl Vandetanib, 4-((4-Bromo-2-fluorophenyl)amino)-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-6-ol, 4-[(4-Bromo-2-fluorophenyl)amino]-7-[(1-methyl-4-piperidinyl)methoxy]-6-quinazolinol.

What is the molecular formula and molecular weight of O-Demethyl Vandetanib?

O-Demethyl Vandetanib has the molecular formula C21H22BrFN4O2 and a molecular weight of 461.3 g/mol. Its IUPAC name is 4-(4-bromo-2-fluoroanilino)-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-6-ol.

What is O-Demethyl Vandetanib used for?

O-Demethyl Vandetanib is supplied as a characterised reference material related to Vandetanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Demethyl Vandetanib can I order?

We supply O-Demethyl Vandetanib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Demethyl Vandetanib?

Yes. Every lot of O-Demethyl Vandetanib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Demethyl Vandetanib be shipped internationally?

Yes. We export O-Demethyl Vandetanib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.