Vandetanib N-Oxide

Name: Vandetanib N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-034542

About Vandetanib N-Oxide

Vandetanib N-Oxide (CAS 1797030-22-8) is a metabolite or degradation product of Vandetanib offered by Vaqora Chemicals. The compound has the formula C22H24BrFN4O3, corresponding to a molecular weight of 491.4 g/mol. Systematically, it is named N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-1-oxidopiperidin-1-ium-4-yl)methoxy]quinazolin-4-amine. It is also known as N-Oxide vandetanib or N-Oxide ZD6474.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Vandetanib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Vandetanib N-Oxide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Vandetanib

View every impurity, metabolite and intermediate we list for Vandetanib.

Vandetanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Vandetanib N-Oxide
Catalogue No.	VQ-034542
CAS Number	1797030-22-8
IUPAC name	N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-1-oxidopiperidin-1-ium-4-yl)methoxy]quinazolin-4-amine
Molecular formula	C₂₂H₂₄BrFN₄O₃
Molecular weight	491.4 g/mol
Exact mass	490.1016
Grade	Reference Standard
HSN code	38229090
InChIKey	CNFXJGPXGDNUHJ-UHFFFAOYSA-N
SMILES	C[N+]1(CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC)[O-]
PubChem CID	99738037

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	1 / 7
TPSA	74.3 Å²
Synonyms	N-Oxide vandetanib, N-Oxide ZD6474, N-Oxide vandetanib metabolite, N-Oxide metabolite of vandetanib, 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-1-oxo-4-yl)methoxy]quinazoline

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Vandetanib N-Oxide?

The CAS Registry Number of Vandetanib N-Oxide is 1797030-22-8. It is also known as N-Oxide vandetanib, N-Oxide ZD6474, N-Oxide vandetanib metabolite.

What is the molecular formula and molecular weight of Vandetanib N-Oxide?

Vandetanib N-Oxide has the molecular formula C22H24BrFN4O3 and a molecular weight of 491.4 g/mol. Its IUPAC name is N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-1-oxidopiperidin-1-ium-4-yl)methoxy]quinazolin-4-amine.

What is Vandetanib N-Oxide used for?

Vandetanib N-Oxide is supplied as a characterised reference material related to Vandetanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Vandetanib N-Oxide can I order?

We supply Vandetanib N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Vandetanib N-Oxide?

Yes. Every lot of Vandetanib N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Vandetanib N-Oxide be shipped internationally?

Yes. We export Vandetanib N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.