O-Desmethyl Apixaban

Name: O-Desmethyl Apixaban
Brand: Vaqora Chemicals
SKU: VQ-020811

About O-Desmethyl Apixaban

Vaqora Chemicals supplies O-Desmethyl Apixaban, a metabolite or degradation product of Apixaban registered under CAS number 503612-76-8. With the molecular formula C24H23N5O4, it has a molar mass of 445.5 g/mol. The IUPAC name is 1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide. Common synonyms include Hydroxy Apixaban and O-Demethyl apixaban.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Apixaban, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer O-Desmethyl Apixaban in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Apixaban

View every impurity, metabolite and intermediate we list for Apixaban.

Apixaban impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desmethyl Apixaban
Catalogue No.	VQ-020811
CAS Number	503612-76-8
IUPAC name	1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide
Molecular formula	C₂₄H₂₃N₅O₄
Molecular weight	445.5 g/mol
Exact mass	445.175
Grade	Reference Standard
HSN code	38229090
InChIKey	HGHLWAZFIGRAOT-UHFFFAOYSA-N
SMILES	C1CCN(C(=O)C1)C2=CC=C(C=C2)N3CCC4=C(C3=O)N(N=C4C(=O)N)C5=CC=C(C=C5)O
PubChem CID	10203943

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 5
TPSA	122 Å²
Synonyms	Hydroxy Apixaban, O-Demethyl apixaban, 4-Demethoxy-4-hydroxy Apixaban, O-DesmethylEApixaban, Apixaban O-Desmethyl Imp, O-Desmethylapixaban (M2)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desmethyl Apixaban?

The CAS Registry Number of O-Desmethyl Apixaban is 503612-76-8. It is also known as Hydroxy Apixaban, O-Demethyl apixaban, 4-Demethoxy-4-hydroxy Apixaban.

What is the molecular formula and molecular weight of O-Desmethyl Apixaban?

O-Desmethyl Apixaban has the molecular formula C24H23N5O4 and a molecular weight of 445.5 g/mol. Its IUPAC name is 1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide.

What is O-Desmethyl Apixaban used for?

O-Desmethyl Apixaban is supplied as a characterised reference material related to Apixaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desmethyl Apixaban can I order?

We supply O-Desmethyl Apixaban in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desmethyl Apixaban?

Yes. Every lot of O-Desmethyl Apixaban is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desmethyl Apixaban be shipped internationally?

Yes. We export O-Desmethyl Apixaban worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.