O-Desmethyl Everolimus

Name: O-Desmethyl Everolimus
Brand: Vaqora Chemicals
SKU: VQ-030636

About O-Desmethyl Everolimus

O-Desmethyl Everolimus (CAS 745779-75-3) is a metabolite or degradation product of Everolimus offered by Vaqora Chemicals. Its molecular formula is C52H81NO14 and its molecular weight is 944.2 g/mol. It is also known as Desmethyl Everolimus or Everolimus 30-O-Desmethyl.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Everolimus, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies O-Desmethyl Everolimus in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Everolimus

View every impurity, metabolite and intermediate we list for Everolimus.

Everolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desmethyl Everolimus
Catalogue No.	VQ-030636
CAS Number	745779-75-3
IUPAC name	(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,30-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular formula	C₅₂H₈₁NO₁₄
Molecular weight	944.2 g/mol
Exact mass	943.5657
Grade	Reference Standard
HSN code	38229090
InChIKey	IENBGEQGDJTPQU-GIZKHTGYSA-N
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)O
PubChem CID	9854474

Physical properties
Physical form	Solid
LogP (XLogP3)	5.3
H-bond donors / acceptors	4 / 14
TPSA	216 Å²
Synonyms	Desmethyl Everolimus, Everolimus 30-O-Desmethyl, 16-O-Demethyl-sdz rad, 16-O-Demethyl-everolimus, 7-O-Demethyl-42-O-(2-hydroxyethyl)rapamycin, Rapamycin, 7-O-demethyl-42-O-(2-hydroxyethyl)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desmethyl Everolimus?

The CAS Registry Number of O-Desmethyl Everolimus is 745779-75-3. It is also known as Desmethyl Everolimus, Everolimus 30-O-Desmethyl, 16-O-Demethyl-sdz rad.

What is the molecular formula and molecular weight of O-Desmethyl Everolimus?

O-Desmethyl Everolimus has the molecular formula C52H81NO14 and a molecular weight of 944.2 g/mol.

What is O-Desmethyl Everolimus used for?

O-Desmethyl Everolimus is supplied as a characterised reference material related to Everolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desmethyl Everolimus can I order?

We supply O-Desmethyl Everolimus in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desmethyl Everolimus?

Yes. Every lot of O-Desmethyl Everolimus is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desmethyl Everolimus be shipped internationally?

Yes. We export O-Desmethyl Everolimus worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.