O-Methyl 12-epi-Dolutegravir

Name: O-Methyl 12-epi-Dolutegravir
Brand: Vaqora Chemicals
SKU: VQ-030266

About O-Methyl 12-epi-Dolutegravir

Listed under CAS 2384108-28-3, O-Methyl 12-epi-Dolutegravir is an impurity of Dolutegravir available from Vaqora Chemicals. Formula C21H21F2N3O5, molecular weight 433.4 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Dolutegravir impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer O-Methyl 12-epi-Dolutegravir in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dolutegravir

View every impurity, metabolite and intermediate we list for Dolutegravir.

Dolutegravir impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Methyl 12-epi-Dolutegravir
Catalogue No.	VQ-030266
CAS Number	2384108-28-3
IUPAC name	(3R,7R)-N-[(2,4-difluorophenyl)methyl]-11-methoxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide
Molecular formula	C₂₁H₂₁F₂N₃O₅
Molecular weight	433.4 g/mol
Exact mass	433.1449
Grade	Reference Standard
HSN code	38229090
InChIKey	MOSMLVZNRGURDI-BDJLRTHQSA-N
SMILES	C[C@@H]1CCO[C@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)OC
PubChem CID	169443417

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 8
TPSA	88.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Methyl 12-epi-Dolutegravir?

The CAS Registry Number of O-Methyl 12-epi-Dolutegravir is 2384108-28-3.

What is the molecular formula and molecular weight of O-Methyl 12-epi-Dolutegravir?

O-Methyl 12-epi-Dolutegravir has the molecular formula C21H21F2N3O5 and a molecular weight of 433.4 g/mol. Its IUPAC name is (3R,7R)-N-[(2,4-difluorophenyl)methyl]-11-methoxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide.

What is O-Methyl 12-epi-Dolutegravir used for?

O-Methyl 12-epi-Dolutegravir is supplied as a characterised reference material related to Dolutegravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Methyl 12-epi-Dolutegravir can I order?

We supply O-Methyl 12-epi-Dolutegravir in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Methyl 12-epi-Dolutegravir?

Yes. Every lot of O-Methyl 12-epi-Dolutegravir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Methyl 12-epi-Dolutegravir be shipped internationally?

Yes. We export O-Methyl 12-epi-Dolutegravir worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.