Papaverine EP Impurity B

Name: Papaverine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-028872

About Papaverine EP Impurity B

Papaverine EP Impurity B is a pharmacopeial impurity of Papaverine carrying the CAS registry number 482-76-8. Formula C20H21NO5, molecular weight 355.4 g/mol. Its systematic (IUPAC) name is (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)methanol. Common synonyms include Papaverine Hydrochloride EP Impurity B and Papaverine Impurity B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Papaverine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Papaverine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Papaverine

View every impurity, metabolite and intermediate we list for Papaverine.

Papaverine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Papaverine EP Impurity B
Catalogue No.	VQ-028872
CAS Number	482-76-8
IUPAC name	(6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)methanol
Molecular formula	C₂₀H₂₁NO₅
Molecular weight	355.4 g/mol
Exact mass	355.142
Grade	Reference Standard
HSN code	38229090
InChIKey	JJZIJKXUHDFVGX-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)C(C2=NC=CC3=CC(=C(C=C32)OC)OC)O)OC
PubChem CID	275192

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 6
TPSA	70 Å²
Synonyms	Papaverine Hydrochloride EP Impurity B, Papaverine Impurity B, Papaverine Hydrochloride - Impurity B, Papaverinol, alpha-(3,4-Dimethoxyphenyl)-6,7-dimethoxy-1-isoquinolinemethanol, alpha-(3,4-Dimethoxyphenyl)-6,7-dimethoxyisoquinoline-1-methanol, (6,7-dimethoxyisoquinolin-1-yl)(3,4-dimethoxyphenyl)methanol, 1-Isoquinolinemethanol,a-(3,4-dimethoxyphenyl)-6,7-dimethoxy-, (6,7-dimethoxyisoquinolyl)(3,4-dimethoxyphenyl)methan-1-ol, 6,7-dimethoxyisoquinolin-1-yl-(3,4-dimethoxyphenyl)carbinol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Papaverine EP Impurity B?

The CAS Registry Number of Papaverine EP Impurity B is 482-76-8. It is also known as Papaverine Hydrochloride EP Impurity B, Papaverine Impurity B, Papaverine Hydrochloride - Impurity B.

What is the molecular formula and molecular weight of Papaverine EP Impurity B?

Papaverine EP Impurity B has the molecular formula C20H21NO5 and a molecular weight of 355.4 g/mol. Its IUPAC name is (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)methanol.

What is Papaverine EP Impurity B used for?

Papaverine EP Impurity B is supplied as a characterised reference material related to Papaverine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Papaverine EP Impurity B can I order?

We supply Papaverine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Papaverine EP Impurity B?

Yes. Every lot of Papaverine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Papaverine EP Impurity B be shipped internationally?

Yes. Papaverine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.