Prochlorperazine EP Impurity A

Name: Prochlorperazine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-023559

About Prochlorperazine EP Impurity A

Prochlorperazine EP Impurity A (CAS 10078-27-0) is a pharmacopeial impurity of Prochlorperazine offered by Vaqora Chemicals. Its molecular formula is C20H24ClN3OS and its molecular weight is 389.9 g/mol. Systematically, it is named (5S)-2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine 5-oxide. Alternative names: Prochlorperazine Sulfoxide and Prochlorperazine 'S' Isomer Impurity.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Prochlorperazine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Prochlorperazine EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Prochlorperazine

View every impurity, metabolite and intermediate we list for Prochlorperazine.

Prochlorperazine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Prochlorperazine EP Impurity A
Catalogue No.	VQ-023559
CAS Number	10078-27-0
IUPAC name	(5S)-2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine 5-oxide
Molecular formula	C₂₀H₂₄ClN₃OS
Molecular weight	389.9 g/mol
Exact mass	389.1329
Grade	Reference Standard
HSN code	38229090
InChIKey	AZGYHFQQUZPAFZ-SANMLTNESA-N
SMILES	CN1CCN(CC1)CCCN2C3=CC=CC=C3[S@](=O)C4=C2C=C(C=C4)Cl
PubChem CID	3084059

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 4
TPSA	56.7 Å²
Synonyms	Prochlorperazine Sulfoxide, Prochlorperazine 'S' Isomer Impurity, Prochlorperazine Maleate - Impurity A, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazine 5-oxide, 10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-, 5-oxide, 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine 5-oxide, 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-, 5-oxide, 10H-Phenothiazine,2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-, 5-oxide, 2-chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine 5-oxide, 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-5lambda~4~-phenothiazin-5(10H)-one

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P261, P263, P264, P270, P271, P280, P301 + P317, P304 + P340, P318, P319, P330, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Prochlorperazine EP Impurity A?

The CAS Registry Number of Prochlorperazine EP Impurity A is 10078-27-0. It is also known as Prochlorperazine Sulfoxide, Prochlorperazine 'S' Isomer Impurity, Prochlorperazine Maleate - Impurity A.

What is the molecular formula and molecular weight of Prochlorperazine EP Impurity A?

Prochlorperazine EP Impurity A has the molecular formula C20H24ClN3OS and a molecular weight of 389.9 g/mol. Its IUPAC name is (5S)-2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine 5-oxide.

What is Prochlorperazine EP Impurity A used for?

Prochlorperazine EP Impurity A is supplied as a characterised reference material related to Prochlorperazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Prochlorperazine EP Impurity A can I order?

We supply Prochlorperazine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Prochlorperazine EP Impurity A?

Yes. Every lot of Prochlorperazine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Prochlorperazine EP Impurity A be shipped internationally?

Yes. Prochlorperazine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.