Progesterone EP Impurity B

Name: Progesterone EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-023567

About Progesterone EP Impurity B

Progesterone EP Impurity B is a pharmacopeial impurity of Progesterone carrying the CAS registry number 145-14-2. The compound has the formula C21H32O2, corresponding to a molecular weight of 316.5 g/mol. It is also known as Progesterone - Impurity B or 20(S)-Hydroxyprogesterone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

This Progesterone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Progesterone EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Progesterone

View every impurity, metabolite and intermediate we list for Progesterone.

Progesterone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Progesterone EP Impurity B
Catalogue No.	VQ-023567
CAS Number	145-14-2
IUPAC name	(8S,9S,10R,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₃₂O₂
Molecular weight	316.5 g/mol
Exact mass	316.2402
Grade	Reference Standard
HSN code	38229090
InChIKey	RWBRUCCWZPSBFC-RXRZZTMXSA-N
SMILES	C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
PubChem CID	8956

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	Progesterone - Impurity B, 20(S)-Hydroxyprogesterone, (20S)-20-Hydroxypregn-4-en-3-one, 20alpha-Dihydroprogesterone, 20alpha-Hydroxyprogesterone, 20-alpha-Dihydroprogesterone, 20-alpha-Hydroxyprogesterone, 20alpha-Hydroxypregn-4-en-3-one, Pregn-4-en-3-one, 20-hydroxy-, (20S)-, 20alpha-Hydroxydihydroprogesterone, (S)-20-Hydroxypregn-4-en-3-one, Pregn-4-en-3-one, 20-alpha-hydroxy-

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Progesterone EP Impurity B?

The CAS Registry Number of Progesterone EP Impurity B is 145-14-2. It is also known as Progesterone - Impurity B, 20(S)-Hydroxyprogesterone, (20S)-20-Hydroxypregn-4-en-3-one.

What is the molecular formula and molecular weight of Progesterone EP Impurity B?

Progesterone EP Impurity B has the molecular formula C21H32O2 and a molecular weight of 316.5 g/mol. Its IUPAC name is (8S,9S,10R,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one.

What is Progesterone EP Impurity B used for?

Progesterone EP Impurity B is supplied as a characterised reference material related to Progesterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Progesterone EP Impurity B can I order?

We supply Progesterone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Progesterone EP Impurity B?

Yes. Every lot of Progesterone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Progesterone EP Impurity B be shipped internationally?

Yes. Progesterone EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.