Pyrazole N-Demethyl Sildenafil

Name: Pyrazole N-Demethyl Sildenafil
Brand: Vaqora Chemicals
SKU: VQ-042166

About Pyrazole N-Demethyl Sildenafil

Vaqora Chemicals supplies Pyrazole N-Demethyl Sildenafil, a metabolite or degradation product of Sildenafil registered under CAS number 139755-95-6. With the molecular formula C21H28N6O4S, it has a molar mass of 460.6 g/mol. Systematically, it is named 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-3-propyl-2,6-dihydropyrazolo[4,3-d]pyrimidin-7-one. Alternative names: Pyrazole N-Desmethyl Sildenafil and Pyrazole N-desmethylsildenafil.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Sildenafil, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Pyrazole N-Demethyl Sildenafil is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Specifications & identifiers

Chemical identifiers
Product name	Pyrazole N-Demethyl Sildenafil
Catalogue No.	VQ-042166
CAS Number	139755-95-6
IUPAC name	5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-3-propyl-2,6-dihydropyrazolo[4,3-d]pyrimidin-7-one
Molecular formula	C₂₁H₂₈N₆O₄S
Molecular weight	460.6 g/mol
Exact mass	460.1893
Grade	Reference Standard
HSN code	38229090
InChIKey	ZLJVUHMTFSCAGQ-UHFFFAOYSA-N
SMILES	CCCC1=C2C(=NN1)C(=O)NC(=N2)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC
PubChem CID	135543792

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 8
TPSA	128 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pyrazole N-Demethyl Sildenafil?

The CAS Registry Number of Pyrazole N-Demethyl Sildenafil is 139755-95-6. It is also known as Pyrazole N-Desmethyl Sildenafil, Pyrazole N-desmethylsildenafil.

What is the molecular formula and molecular weight of Pyrazole N-Demethyl Sildenafil?

Pyrazole N-Demethyl Sildenafil has the molecular formula C21H28N6O4S and a molecular weight of 460.6 g/mol. Its IUPAC name is 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-3-propyl-2,6-dihydropyrazolo[4,3-d]pyrimidin-7-one.

What is Pyrazole N-Demethyl Sildenafil used for?

Pyrazole N-Demethyl Sildenafil is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pyrazole N-Demethyl Sildenafil can I order?

We supply Pyrazole N-Demethyl Sildenafil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pyrazole N-Demethyl Sildenafil?

Yes. Every lot of Pyrazole N-Demethyl Sildenafil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pyrazole N-Demethyl Sildenafil be shipped internationally?

Yes. We export Pyrazole N-Demethyl Sildenafil worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.