Thiohomosildenafil

Name: Thiohomosildenafil
Brand: Vaqora Chemicals
SKU: VQ-042160

About Thiohomosildenafil

Thiohomosildenafil is an impurity of Sildenafil carrying the CAS registry number 479073-80-8. With the molecular formula C23H32N6O3S2, it has a molar mass of 504.7 g/mol. The IUPAC name is 5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,5-d]pyrimidine-7-thione. Alternative names: Homosildenafil thione.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Sildenafil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Thiohomosildenafil in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Specifications & identifiers

Chemical identifiers
Product name	Thiohomosildenafil
Catalogue No.	VQ-042160
CAS Number	479073-80-8
IUPAC name	5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,5-d]pyrimidine-7-thione
Molecular formula	C₂₃H₃₂N₆O₃S₂
Molecular weight	504.7 g/mol
Exact mass	504.1977
Grade	Reference Standard
HSN code	38229090
InChIKey	BGPSRMUUQQTZFB-UHFFFAOYSA-N
SMILES	CCCC1=NN(C2=C1NC(=NC2=S)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C
PubChem CID	10207456

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 7
TPSA	133 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiohomosildenafil?

The CAS Registry Number of Thiohomosildenafil is 479073-80-8. It is also known as Homosildenafil thione.

What is the molecular formula and molecular weight of Thiohomosildenafil?

Thiohomosildenafil has the molecular formula C23H32N6O3S2 and a molecular weight of 504.7 g/mol. Its IUPAC name is 5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,5-d]pyrimidine-7-thione.

What is Thiohomosildenafil used for?

Thiohomosildenafil is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiohomosildenafil can I order?

We supply Thiohomosildenafil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiohomosildenafil?

Yes. Every lot of Thiohomosildenafil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiohomosildenafil be shipped internationally?

Yes. We export Thiohomosildenafil worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.