Quetiapine EP Impurity I

Name: Quetiapine EP Impurity I
Brand: Vaqora Chemicals
SKU: VQ-006618

About Quetiapine EP Impurity I

Listed under CAS 329216-67-3, Quetiapine EP Impurity I is a pharmacopeial impurity of Quetiapine available from Vaqora Chemicals at a purity of 97.15%. The compound has the formula C19H21N3OS, corresponding to a molecular weight of 339.5 g/mol. The IUPAC name is 2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethanol. Alternative names: Quetiapine Hydroxy Impurity and 2-4-(2-Hydroxyethyl)piperazin-1-yldithiazepin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Quetiapine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Quetiapine EP Impurity I in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Quetiapine EP Impurity I
Catalogue No.	VQ-006618
CAS Number	329216-67-3
IUPAC name	2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethanol
Molecular formula	C₁₉H₂₁N₃OS
Molecular weight	339.5 g/mol
Exact mass	339.1405
Grade	Reference Standard
Purity / assay	97.15%
HSN code	38229090
InChIKey	OFLMIXVKBNAUIB-UHFFFAOYSA-N
SMILES	C1CN(CCN1CCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42
PubChem CID	10807021

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 4
TPSA	64.4 Å²
Synonyms	Quetiapine Hydroxy Impurity, 2-4-(2-Hydroxyethyl)piperazin-1-yldithiazepin, Des-hydroxyethyl Quetiapine, 4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol, 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethanol, Quetiapine Desethanol, Quetiapine Fumarate Impurity A (IP), 2-(4-(Dibenzo(b,f)(1,4)thiazepin-11-yl)piperazin-1-yl) ethanol, 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl] ethanol, 4-Dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazineethanol, Quetiapine Hydroxy Impurity Dihydrochloride Salt, Quetiapine Impurity I

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P319, P330, P337 + P317, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Quetiapine EP Impurity I?

The CAS Registry Number of Quetiapine EP Impurity I is 329216-67-3. It is also known as Quetiapine Hydroxy Impurity, 2-4-(2-Hydroxyethyl)piperazin-1-yldithiazepin, Des-hydroxyethyl Quetiapine.

What is the molecular formula and molecular weight of Quetiapine EP Impurity I?

Quetiapine EP Impurity I has the molecular formula C19H21N3OS and a molecular weight of 339.5 g/mol. Its IUPAC name is 2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethanol.

What is Quetiapine EP Impurity I used for?

Quetiapine EP Impurity I is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Quetiapine EP Impurity I can I order?

We supply Quetiapine EP Impurity I in Reference Standard (97.15%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Quetiapine EP Impurity I?

Yes. Every lot of Quetiapine EP Impurity I is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Quetiapine EP Impurity I be shipped internationally?

Yes. Quetiapine EP Impurity I is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.