Quetiapine Hemifumarate

Name: Quetiapine Hemifumarate
Brand: Vaqora Chemicals
SKU: VQ-007687

About Quetiapine Hemifumarate

Quetiapine Hemifumarate is a high-purity reference standard of Quetiapine carrying the CAS registry number 111974-72-2. The compound has the formula C46H54N6O8S2, corresponding to a molecular weight of 883.1 g/mol. The IUPAC name is bis(2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol), (E)-but-2-enedioic acid. Common synonyms include Kwetaplex and Loquen.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Quetiapine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Quetiapine Hemifumarate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Specifications & identifiers

Chemical identifiers
Product name	Quetiapine Hemifumarate
Catalogue No.	VQ-007687
CAS Number	111974-72-2
Other CAS	111974-69-7, 930086-71-8
IUPAC name	bis(2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol);(E)-but-2-enedioic acid
Molecular formula	C₄₆H₅₄N₆O₈S₂
Molecular weight	883.1 g/mol
Exact mass	882.3445
Grade	Reference Standard
HSN code	38229090
InChIKey	ZTHJULTYCAQOIJ-WXXKFALUSA-N
SMILES	C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C(=C/C(=O)O)\C(=O)O
PubChem CID	5281025

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 14
TPSA	222 Å²
Synonyms	Kwetaplex, Loquen, Quetiapine fumarate, Seroquel, Seroquel XR, Utapine, Quetiapine (as fumarate), FK947E, FK-947E, 2-(2-(4-Dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol, Quetiapine Fumarate ER, Quetiapine Extended-release

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H400Very toxic to aquatic life
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P321, P330, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 111974-72-2

IP/BP/USP

Quetiapine Fumarate

CAS: 111974-72-2
Formula: C₄₆H₅₄N₆O₈S₂
MW: 883.1 g/mol

VQ-004057

Frequently asked questions

What is the CAS number of Quetiapine Hemifumarate?

The CAS Registry Number of Quetiapine Hemifumarate is 111974-72-2. It is also known as Kwetaplex, Loquen, Quetiapine fumarate.

What is the molecular formula and molecular weight of Quetiapine Hemifumarate?

Quetiapine Hemifumarate has the molecular formula C46H54N6O8S2 and a molecular weight of 883.1 g/mol.

What is Quetiapine Hemifumarate used for?

Quetiapine Hemifumarate is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Quetiapine Hemifumarate can I order?

We supply Quetiapine Hemifumarate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Quetiapine Hemifumarate?

Yes. Every lot of Quetiapine Hemifumarate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Quetiapine Hemifumarate be shipped internationally?

Yes. Quetiapine Hemifumarate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.