(R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(… 1801651-84-2

Name: (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
Brand: Vaqora Chemicals
SKU: VQ-045008

About (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine

Vaqora Chemicals supplies (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine, an impurity of Crizotinib registered under CAS number 1801651-84-2. Its molecular formula is C21H23ClFN5O and its molecular weight is 415.9 g/mol. Systematically, it is named 3-[(1R)-1-(2-chloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Crizotinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Crizotinib

View every impurity, metabolite and intermediate we list for Crizotinib.

Crizotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
Catalogue No.	VQ-045008
CAS Number	1801651-84-2
IUPAC name	3-[(1R)-1-(2-chloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
Molecular formula	C₂₁H₂₃ClFN₅O
Molecular weight	415.9 g/mol
Exact mass	415.1575
Grade	Reference Standard
HSN code	38229090
InChIKey	KWCJDWZKVHOTBP-CYBMUJFWSA-N
SMILES	C[C@H](C1=C(C(=CC=C1)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
PubChem CID	144887703

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	2 / 6
TPSA	78 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine?

The CAS Registry Number of (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine is 1801651-84-2.

What is the molecular formula and molecular weight of (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine?

(R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine has the molecular formula C21H23ClFN5O and a molecular weight of 415.9 g/mol. Its IUPAC name is 3-[(1R)-1-(2-chloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine.

What is (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine used for?

(R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine is supplied as a characterised reference material related to Crizotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine can I order?

We supply (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine?

Yes. Every lot of (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine be shipped internationally?

Yes. We export (R)-3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.