(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) 1395950-84-1

Name: (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
Brand: Vaqora Chemicals
SKU: VQ-029940

About (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)

Listed under CAS 1395950-84-1, (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) is a stable isotope labelled analogue related to Crizotinib available from Vaqora Chemicals. Its molecular formula is C21H22Cl2FN5O and its molecular weight is 455.4 g/mol. Common synonyms include (R)-Crizotinib-D5 and Crizotinib D5.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Crizotinib

View every impurity, metabolite and intermediate we list for Crizotinib.

Crizotinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
Catalogue No.	VQ-029940
CAS Number	1395950-84-1
IUPAC name	3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(3,3,4,5,5-pentadeuteriopiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
Molecular formula	C₂₁H₂₂Cl₂FN₅O
Molecular weight	455.4 g/mol
Exact mass	454.1499
Grade	Reference Standard
HSN code	38229090
InChIKey	KTEIFNKAUNYNJU-LJIFSARKSA-N
SMILES	[2H]C1(CNCC(C1([2H])N2C=C(C=N2)C3=CC(=C(N=C3)N)O[C@H](C)C4=C(C=CC(=C4Cl)F)Cl)([2H])[2H])[2H]
PubChem CID	156588737

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 6
TPSA	78 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)?

The CAS Registry Number of (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) is 1395950-84-1. It is also known as (R)-Crizotinib-D5, Crizotinib D5, Crizotinib-d5.

What is the molecular formula and molecular weight of (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)?

(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) has the molecular formula C21H22Cl2FN5O and a molecular weight of 455.4 g/mol. Its IUPAC name is 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(3,3,4,5,5-pentadeuteriopiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine.

What is (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) used for?

(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) is supplied as a characterised reference material related to Crizotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) can I order?

We supply (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)?

Yes. Every lot of (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) be shipped internationally?

Yes. We export (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.