(R)-Elexacaftor

Name: (R)-Elexacaftor
Brand: Vaqora Chemicals
SKU: VQ-025508

About (R)-Elexacaftor

(R)-Elexacaftor (CAS 2229860-99-3) is a high-purity reference standard of Elexacaftor offered by Vaqora Chemicals. With the molecular formula C26H34F3N7O4S, it has a molar mass of 597.7 g/mol. Common synonyms include VX-445 R enantiomer and (R)-Elexacaftor(R)-VX-445.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a reference sample of Elexacaftor, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-Elexacaftor is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Elexacaftor

View every impurity, metabolite and intermediate we list for Elexacaftor.

Elexacaftor impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Elexacaftor
Catalogue No.	VQ-025508
CAS Number	2229860-99-3
IUPAC name	N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4R)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
Molecular formula	C₂₆H₃₄F₃N₇O₄S
Molecular weight	597.7 g/mol
Exact mass	597.2345
Grade	Reference Standard
HSN code	38229090
InChIKey	MVRHVFSOIWFBTE-MRXNPFEDSA-N
SMILES	C[C@@H]1CC(N(C1)C2=C(C=CC(=N2)N3C=CC(=N3)OCC(C)(C)C(F)(F)F)C(=O)NS(=O)(=O)C4=CN(N=C4C)C)(C)C
PubChem CID	134587287

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 11
TPSA	133 Å²
Synonyms	VX-445 R enantiomer, (R)-Elexacaftor(R)-VX-445, EX-A3639, VX-445(R), (R)-VX-445

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Elexacaftor?

The CAS Registry Number of (R)-Elexacaftor is 2229860-99-3. It is also known as VX-445 R enantiomer, (R)-Elexacaftor(R)-VX-445, EX-A3639.

What is the molecular formula and molecular weight of (R)-Elexacaftor?

(R)-Elexacaftor has the molecular formula C26H34F3N7O4S and a molecular weight of 597.7 g/mol. Its IUPAC name is N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4R)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide.

What is (R)-Elexacaftor used for?

(R)-Elexacaftor is supplied as a characterised reference material related to Elexacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Elexacaftor can I order?

We supply (R)-Elexacaftor in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Elexacaftor?

Yes. Every lot of (R)-Elexacaftor is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Elexacaftor be shipped internationally?

Yes. We export (R)-Elexacaftor worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.