(R)-(+)-3-Aminoquinuclidine Dihydrochloride 123536-14-1

Name: (R)-(+)-3-Aminoquinuclidine Dihydrochloride
Brand: Vaqora Chemicals
SKU: VQ-049648

About (R)-(+)-3-Aminoquinuclidine Dihydrochloride

Listed under CAS 123536-14-1, (R)-(+)-3-Aminoquinuclidine Dihydrochloride is a process intermediate or related compound of Palonosetron available from Vaqora Chemicals. With the molecular formula C7H16Cl2N2, it has a molar mass of 199.12 g/mol. Alternative names: (3R)-Aminoquinuclidine Dihydrochloride and (R)-quinuclidin-3-amine dihydrochloride.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Palonosetron, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (R)-(+)-3-Aminoquinuclidine Dihydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-(+)-3-Aminoquinuclidine Dihydrochloride
Catalogue No.	VQ-049648
CAS Number	123536-14-1
IUPAC name	(3R)-1-azabicyclo[2.2.2]octan-3-amine;dihydrochloride
Molecular formula	C₇H₁₆Cl₂N₂
Molecular weight	199.12 g/mol
Exact mass	198.0691
HSN code	2933
InChIKey	STZHBULOYDCZET-KLXURFKVSA-N
SMILES	C1CN2CCC1[C@H](C2)N.Cl.Cl
PubChem CID	12494972

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 2
TPSA	29.3 Å²
Synonyms	(3R)-Aminoquinuclidine Dihydrochloride, (3R)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride, (R)-quinuclidin-3-amine dihydrochloride, (3R)-Quinuclidin-3-amine dihydrochloride, 1-Azabicyclo[2.2.2]octan-3-amine, hydrochloride (1:2), (3R)-, (R)-(+)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride, (r)-1-aza-bicyclo[2.2.2]oct-3-ylamine dihydrochloride, (3R)-1-azabicyclo[2.2.2]octan-3-amine hydrochloride, 1-Azabicyclo[2.2.2]octan-3-amine, dihydrochloride, (3R)-, (R)-3-Aminoquinuclidine diHCl

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-(+)-3-Aminoquinuclidine Dihydrochloride?

The CAS Registry Number of (R)-(+)-3-Aminoquinuclidine Dihydrochloride is 123536-14-1. It is also known as (3R)-Aminoquinuclidine Dihydrochloride, (3R)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride, (R)-quinuclidin-3-amine dihydrochloride.

What is the molecular formula and molecular weight of (R)-(+)-3-Aminoquinuclidine Dihydrochloride?

(R)-(+)-3-Aminoquinuclidine Dihydrochloride has the molecular formula C7H16Cl2N2 and a molecular weight of 199.12 g/mol.

What is (R)-(+)-3-Aminoquinuclidine Dihydrochloride used for?

(R)-(+)-3-Aminoquinuclidine Dihydrochloride is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-(+)-3-Aminoquinuclidine Dihydrochloride can I order?

We supply (R)-(+)-3-Aminoquinuclidine Dihydrochloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-(+)-3-Aminoquinuclidine Dihydrochloride?

Yes. Every lot of (R)-(+)-3-Aminoquinuclidine Dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-(+)-3-Aminoquinuclidine Dihydrochloride be shipped internationally?

Yes. (R)-(+)-3-Aminoquinuclidine Dihydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.