Ramipril EP Impurity D

Name: Ramipril EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-027740

About Ramipril EP Impurity D

Ramipril EP Impurity D is a pharmacopeial impurity of Ramipril carrying the CAS registry number 108731-95-9. Formula C23H30N2O4, molecular weight 398.5 g/mol. It is also known as Ramipril - Impurity D or Ramipril Diketopiperazine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Ramipril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Ramipril EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ramipril

View every impurity, metabolite and intermediate we list for Ramipril.

Ramipril impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ramipril EP Impurity D
Catalogue No.	VQ-027740
CAS Number	108731-95-9
IUPAC name	ethyl (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoate
Molecular formula	C₂₃H₃₀N₂O₄
Molecular weight	398.5 g/mol
Exact mass	398.2206
Grade	Reference Standard
HSN code	38229090
InChIKey	KOVMAAYRBJCASY-JBDAPHQKSA-N
SMILES	CCOC(=O)[C@H](CCC1=CC=CC=C1)N2[C@H](C(=O)N3[C@H]4CCC[C@H]4C[C@H]3C2=O)C
PubChem CID	14520363

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	0 / 4
TPSA	66.9 Å²
Synonyms	Ramipril - Impurity D, Ramipril Diketopiperazine, Ramipril-diketopiperazine, Ramipril specified impurity D, Ramipril impurity

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ramipril EP Impurity D?

The CAS Registry Number of Ramipril EP Impurity D is 108731-95-9. It is also known as Ramipril - Impurity D, Ramipril Diketopiperazine, Ramipril-diketopiperazine.

What is the molecular formula and molecular weight of Ramipril EP Impurity D?

Ramipril EP Impurity D has the molecular formula C23H30N2O4 and a molecular weight of 398.5 g/mol. Its IUPAC name is ethyl (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoate.

What is Ramipril EP Impurity D used for?

Ramipril EP Impurity D is supplied as a characterised reference material related to Ramipril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ramipril EP Impurity D can I order?

We supply Ramipril EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ramipril EP Impurity D?

Yes. Every lot of Ramipril EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ramipril EP Impurity D be shipped internationally?

Yes. Ramipril EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.