Rapamycin

Name: Rapamycin
Brand: Vaqora Chemicals
SKU: VQ-007698

About Rapamycin

Listed under CAS 53123-88-9, Rapamycin is a high-purity reference standard of Rapamycin available from Vaqora Chemicals. Its molecular formula is C51H79NO13 and its molecular weight is 914.2 g/mol. Alternative names: (-)-Rapamycin and Antibiotic AY 22989.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Rapamycin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rapamycin in 5 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Rapamycin

View every impurity, metabolite and intermediate we list for Rapamycin.

Rapamycin impurities

Specifications & identifiers

Chemical identifiers
Product name	Rapamycin
Catalogue No.	VQ-007698
CAS Number	53123-88-9
IUPAC name	(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular formula	C₅₁H₇₉NO₁₃
Molecular weight	914.2 g/mol
Exact mass	913.5551
Grade	Reference Standard
HSN code	38229090
InChIKey	QFJCIRLUMZQUOT-HPLJOQBZSA-N
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
PubChem CID	5284616

Physical properties
Physical form	Solid
LogP (XLogP3)	6
H-bond donors / acceptors	3 / 13
TPSA	195 Å²
Synonyms	(-)-Rapamycin, Antibiotic AY 22989, Cypher, RAPA, RPM, Rapammune, Rapamune, SIIA 9268A, Sirolimus, Npc-12g, SILA 9268A, Rapamycin (Sirolimus)

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H341Suspected of causing genetic defects
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 53123-88-9

Rapamycin, ≥98% (HPLC)

CAS: 53123-88-9
Formula: C₅₁H₇₉NO₁₃
MW: 914.2 g/mol

VQ-003750

Cell Culture

Rapamycin, cell culture tested

CAS: 53123-88-9
Formula: C₅₁H₇₉NO₁₃
MW: 914.2 g/mol

VQ-046462

Rapamycin, from streptomyces hygroscopicus

CAS: 53123-88-9
Formula: C₅₁H₇₉NO₁₃
MW: 914.2 g/mol

VQ-003749

Frequently asked questions

What is the CAS number of Rapamycin?

The CAS Registry Number of Rapamycin is 53123-88-9. It is also known as (-)-Rapamycin, Antibiotic AY 22989, Cypher.

What is the molecular formula and molecular weight of Rapamycin?

Rapamycin has the molecular formula C51H79NO13 and a molecular weight of 914.2 g/mol.

What is Rapamycin used for?

Rapamycin is supplied as a characterised reference material related to Rapamycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rapamycin can I order?

We supply Rapamycin in Reference Standard grade, in 5 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rapamycin?

Yes. Every lot of Rapamycin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rapamycin be shipped internationally?

Yes. Rapamycin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.