Rapamycin-D3

Name: Rapamycin-D3
Brand: Vaqora Chemicals
SKU: VQ-042192

About Rapamycin-D3

Rapamycin-D3 (CAS 392711-19-2) is a stable isotope labelled analogue related to Sirolimus offered by Vaqora Chemicals. The compound has the formula C51H79NO13, corresponding to a molecular weight of 917.2 g/mol. Common synonyms include SiroliMus-D3/RapaMycin-D3.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rapamycin-D3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Sirolimus

View every impurity, metabolite and intermediate we list for Sirolimus.

Sirolimus impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Rapamycin-D3
Catalogue No.	VQ-042192
CAS Number	392711-19-2
IUPAC name	(1R,9S,12S,15R,16E,18R,19R,21R,23S,24Z,26Z,28Z,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19-methoxy-15,17,21,23,29,35-hexamethyl-30-(trideuteriomethoxy)-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular formula	C₅₁H₇₉NO₁₃
Molecular weight	917.2 g/mol
Exact mass	916.574
Grade	Reference Standard
HSN code	38229090
InChIKey	QFJCIRLUMZQUOT-STESSXJYSA-N
SMILES	[2H]C([2H])([2H])O[C@H]/1C[C@@H]2CC[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H](CC(=O)[C@@H](/C=C(/[C@H]([C@H](C(=O)[C@@H](C[C@@H](/C=C\C=C/C=C1/C)C)C)OC)O)\C)C)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)O)C
PubChem CID	155908783

Physical properties
Physical form	Solid
LogP (XLogP3)	6
H-bond donors / acceptors	3 / 13
TPSA	195 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rapamycin-D3?

The CAS Registry Number of Rapamycin-D3 is 392711-19-2. It is also known as SiroliMus-D3/RapaMycin-D3.

What is the molecular formula and molecular weight of Rapamycin-D3?

Rapamycin-D3 has the molecular formula C51H79NO13 and a molecular weight of 917.2 g/mol.

What is Rapamycin-D3 used for?

Rapamycin-D3 is supplied as a characterised reference material related to Sirolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rapamycin-D3 can I order?

We supply Rapamycin-D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rapamycin-D3?

Yes. Every lot of Rapamycin-D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rapamycin-D3 be shipped internationally?

Yes. We export Rapamycin-D3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.