(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-meth… 2459446-56-9

Name: (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid
Brand: Vaqora Chemicals
SKU: VQ-033723

About (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid

(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid (CAS 2459446-56-9) is an impurity of Sacubitril offered by Vaqora Chemicals. The compound has the formula C18H19NO2, corresponding to a molecular weight of 281.3 g/mol. Systematically, it is named (E,4R)-4-amino-2-methyl-5-(4-phenylphenyl)pent-2-enoic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Sacubitril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid
Catalogue No.	VQ-033723
CAS Number	2459446-56-9
IUPAC name	(E,4R)-4-amino-2-methyl-5-(4-phenylphenyl)pent-2-enoic acid
Molecular formula	C₁₈H₁₉NO₂
Molecular weight	281.3 g/mol
Exact mass	281.1416
Grade	Reference Standard
HSN code	38229090
InChIKey	DEHVZILALHRVLM-HVJHFUJKSA-N
SMILES	C/C(=C\[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)N)/C(=O)O
PubChem CID	87059476

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	2 / 3
TPSA	63.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid?

The CAS Registry Number of (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid is 2459446-56-9. It is also known as (2E,4R)-4-Amino-5-[1,1'-biphenyl]-4-yl-2-methyl-2-pentenoic acid, 2-Pentenoic acid, 4-amino-5-[1,1'-biphenyl]-4-yl-2-methyl-, (2E,4R)-.

What is the molecular formula and molecular weight of (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid?

(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid has the molecular formula C18H19NO2 and a molecular weight of 281.3 g/mol. Its IUPAC name is (E,4R)-4-amino-2-methyl-5-(4-phenylphenyl)pent-2-enoic acid.

What is (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid used for?

(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid can I order?

We supply (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid?

Yes. Every lot of (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid be shipped internationally?

Yes. We export (R,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.