Regorafenib-13C-D3

Name: Regorafenib-13C-D3
Brand: Vaqora Chemicals
SKU: VQ-041858

About Regorafenib-13C-D3

Vaqora Chemicals supplies Regorafenib-13C-D3, a stable isotope labelled analogue related to Regorafenib registered under CAS number 2126178-55-8. Formula C21H15ClF4N4O3, molecular weight 486.8 g/mol. Alternative names: TMIJ-0124.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Regorafenib and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Regorafenib-13C-D3
Catalogue No.	VQ-041858
CAS Number	2126178-55-8
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-(trideuterio(113C)methyl)pyridine-2-carboxamide
Molecular formula	C₂₁H₁₅ClF₄N₄O₃
Molecular weight	486.8 g/mol
Exact mass	486.0991
Grade	Reference Standard
HSN code	38229090
InChIKey	FNHKPVJBJVTLMP-KQORAOOSSA-N
SMILES	[2H][13C]([2H])([2H])NC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
PubChem CID	76974621

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	3 / 8
TPSA	92.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Regorafenib-13C-D3?

The CAS Registry Number of Regorafenib-13C-D3 is 2126178-55-8. It is also known as TMIJ-0124.

What is the molecular formula and molecular weight of Regorafenib-13C-D3?

Regorafenib-13C-D3 has the molecular formula C21H15ClF4N4O3 and a molecular weight of 486.8 g/mol. Its IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-(trideuterio(113C)methyl)pyridine-2-carboxamide.

What is Regorafenib-13C-D3 used for?

Regorafenib-13C-D3 is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Regorafenib-13C-D3 can I order?

We supply Regorafenib-13C-D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Regorafenib-13C-D3?

Yes. Every lot of Regorafenib-13C-D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Regorafenib-13C-D3 be shipped internationally?

Yes. We export Regorafenib-13C-D3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.