Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenyl… 131968-74-6

Name: Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate
Brand: Vaqora Chemicals
SKU: VQ-048056

About Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate

Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate (CAS 131968-74-6) is a metabolite or degradation product of Docetaxel offered by Vaqora Chemicals. Its molecular formula is C10H13NO3 and its molecular weight is 195.21 g/mol. The IUPAC name is methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate. Alternative names: (2R,3S)-3-Phenylisoserine methyl ester and (2R,3S)-beta-phenyl isoserine methyl ester.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Docetaxel, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Docetaxel

View every impurity, metabolite and intermediate we list for Docetaxel.

Docetaxel impurities

Specifications & identifiers

Chemical identifiers
Product name	Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate
Catalogue No.	VQ-048056
CAS Number	131968-74-6
IUPAC name	methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate
Molecular formula	C₁₀H₁₃NO₃
Molecular weight	195.21 g/mol
Exact mass	195.0895
Grade	Reference Standard
HSN code	38229090
InChIKey	WZPZWAQKLOPJEL-DTWKUNHWSA-N
SMILES	COC(=O)[C@@H]([C@H](C1=CC=CC=C1)N)O
PubChem CID	10176516

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	2 / 4
TPSA	72.6 Å²
Synonyms	(2R,3S)-3-Phenylisoserine methyl ester, (2R,3S)-Methyl 3-amino-2-hydroxy-3-phenylpropanoate, Benzenepropanoic acid, beta-amino-alpha-hydroxy-, methyl ester, (alphaR,betaS)-rel-, (2R,3S)-beta-phenyl isoserine methyl ester, (2R,3S)-beta-phenyl-isoserine methyl ester, (2R,3S)-Methyl3-amino-2-hydroxy-3-phenylpropanoate, methyl (2R,3S)-3-amino-2-hydroxy-3-phenyl-propanoate, Benzenepropanoic acid,, A-amino-, A-hydroxy-, methyl ester, (, AR,, AS)-rel-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate?

The CAS Registry Number of Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate is 131968-74-6. It is also known as (2R,3S)-3-Phenylisoserine methyl ester, (2R,3S)-Methyl 3-amino-2-hydroxy-3-phenylpropanoate, Benzenepropanoic acid, beta-amino-alpha-hydroxy-, methyl ester, (alphaR,betaS)-rel-.

What is the molecular formula and molecular weight of Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate?

Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate has the molecular formula C10H13NO3 and a molecular weight of 195.21 g/mol. Its IUPAC name is methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate.

What is Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate used for?

Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate is supplied as a characterised reference material related to Docetaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate can I order?

We supply Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate?

Yes. Every lot of Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate be shipped internationally?

Yes. Rel-Methyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.