Ribociclib Chloro Amide Impurity

Name: Ribociclib Chloro Amide Impurity
Brand: Vaqora Chemicals
SKU: VQ-027790

About Ribociclib Chloro Amide Impurity

Ribociclib Chloro Amide Impurity (CAS 1211443-61-6) is an impurity of Ribociclib offered by Vaqora Chemicals. With the molecular formula C14H17ClN4O, it has a molar mass of 292.76 g/mol. The IUPAC name is 2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo[2,3-d]pyrimidine-6-carboxamide. Common synonyms include CS-B1515.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Ribociclib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ribociclib Chloro Amide Impurity
Catalogue No.	VQ-027790
CAS Number	1211443-61-6
IUPAC name	2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo[2,3-d]pyrimidine-6-carboxamide
Molecular formula	C₁₄H₁₇ClN₄O
Molecular weight	292.76 g/mol
Exact mass	292.1091
Grade	Reference Standard
HSN code	38229090
InChIKey	PMDDQOHZLBZUSO-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)Cl
PubChem CID	58315432

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 3
TPSA	51 Å²
Synonyms	2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo(2,3-d)pyrimidine-6-carboxamide, 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-, 7H-Pyrrolo(2,3-d)pyrimidine-6-carboxamide, 2-chloro-7-cyclopentyl-N,N-dimethyl-, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide, CS-B1515, 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-c, 2-chloro-7-cyclopentyl-N,N-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamide, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethyl amide, IThorn2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo[2,3-d]pyrimidine-6-carboxamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H402Harmful to aquatic life
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P321, P330, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ribociclib Chloro Amide Impurity?

The CAS Registry Number of Ribociclib Chloro Amide Impurity is 1211443-61-6. It is also known as 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo(2,3-d)pyrimidine-6-carboxamide, 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-.

What is the molecular formula and molecular weight of Ribociclib Chloro Amide Impurity?

Ribociclib Chloro Amide Impurity has the molecular formula C14H17ClN4O and a molecular weight of 292.76 g/mol. Its IUPAC name is 2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo[2,3-d]pyrimidine-6-carboxamide.

What is Ribociclib Chloro Amide Impurity used for?

Ribociclib Chloro Amide Impurity is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ribociclib Chloro Amide Impurity can I order?

We supply Ribociclib Chloro Amide Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ribociclib Chloro Amide Impurity?

Yes. Every lot of Ribociclib Chloro Amide Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ribociclib Chloro Amide Impurity be shipped internationally?

Yes. Ribociclib Chloro Amide Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.