Ribociclib Succinate

Name: Ribociclib Succinate
Brand: Vaqora Chemicals
SKU: VQ-007709

About Ribociclib Succinate

Listed under CAS 1374639-75-4, Ribociclib Succinate is a high-purity reference standard of Ribociclib available from Vaqora Chemicals. With the molecular formula C27H36N8O5, it has a molar mass of 552.6 g/mol. Common synonyms include LEE 011 Succinate and LEE-011 succinate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Ribociclib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Ribociclib Succinate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ribociclib Succinate
Catalogue No.	VQ-007709
CAS Number	1374639-75-4
Other CAS	1211441-98-3, 1374639-79-8
IUPAC name	butanedioic acid;7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
Molecular formula	C₂₇H₃₆N₈O₅
Molecular weight	552.6 g/mol
Exact mass	552.2809
Grade	Reference Standard
HSN code	38229090
InChIKey	NHANOMFABJQAAH-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.C(CC(=O)O)C(=O)O
PubChem CID	57334219

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 11
TPSA	166 Å²
Synonyms	LEE 011 Succinate, LEE-011 succinate, LEE011 succinate, Ribociclib succinate (USAN), Kisqali (TN), LEE011 succinate?, EX-A1586, LEE-011 succinate salt, Ribociclib succinate salt

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P264 + P265, P270, P273, P280, P301 + P316, P302 + P352, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ribociclib Succinate?

The CAS Registry Number of Ribociclib Succinate is 1374639-75-4. It is also known as LEE 011 Succinate, LEE-011 succinate, LEE011 succinate.

What is the molecular formula and molecular weight of Ribociclib Succinate?

Ribociclib Succinate has the molecular formula C27H36N8O5 and a molecular weight of 552.6 g/mol.

What is Ribociclib Succinate used for?

Ribociclib Succinate is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ribociclib Succinate can I order?

We supply Ribociclib Succinate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ribociclib Succinate?

Yes. Every lot of Ribociclib Succinate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ribociclib Succinate be shipped internationally?

Yes. Ribociclib Succinate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.