Riociguat

Name: Riociguat
Brand: Vaqora Chemicals
SKU: VQ-007719

About Riociguat

Riociguat is a high-purity reference standard of Riociguat carrying the CAS registry number 625115-55-1. With the molecular formula C20H19FN8O2, it has a molar mass of 422.4 g/mol. Common synonyms include Adempas and Riociguat (BAY 63-2521).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a reference sample of Riociguat, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Riociguat in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Riociguat

View every impurity, metabolite and intermediate we list for Riociguat.

Riociguat impurities

Specifications & identifiers

Chemical identifiers
Product name	Riociguat
Catalogue No.	VQ-007719
CAS Number	625115-55-1
IUPAC name	methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate
Molecular formula	C₂₀H₁₉FN₈O₂
Molecular weight	422.4 g/mol
Exact mass	422.1615
Grade	Reference Standard
HSN code	38229090
InChIKey	WXXSNCNJFUAIDG-UHFFFAOYSA-N
SMILES	CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC
PubChem CID	11304743

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	2 / 9
TPSA	138 Å²
Synonyms	Adempas, Riociguat (BAY 63-2521), EX-A2023, Riociguate, Riociguat CRS, Adempas (TN), Riociguat (Standard), RiociguatBAY 632521, Riociguat (JAN/USAN/INN), methyl N-[4,6-diamino-2-[1, Riociguat (BAY 63-2521)?, Riociguat,CAS:625115-55-1

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Riociguat?

The CAS Registry Number of Riociguat is 625115-55-1. It is also known as Adempas, Riociguat (BAY 63-2521), EX-A2023.

What is the molecular formula and molecular weight of Riociguat?

Riociguat has the molecular formula C20H19FN8O2 and a molecular weight of 422.4 g/mol. Its IUPAC name is methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate.

What is Riociguat used for?

Riociguat is supplied as a characterised reference material related to Riociguat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Riociguat can I order?

We supply Riociguat in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Riociguat?

Yes. Every lot of Riociguat is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Riociguat be shipped internationally?

Yes. Riociguat is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.