![(E)-2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(phenyldiazenyl)pyrimidine-4,6-diamine chemical structure](/media/structures/NSYPPYLRJKGGOV-UHFFFAOYSA-N.svg)
(E)-2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(phenyldiazenyl)pyrimidine-4,6-diamine
- CAS
- 370879-49-5
- Formula
- C23H18FN9
- MW
- 439.4 g/mol
VQ-041920
Impurity reference standards
Riociguat impurities & reference standards
Characterised Riociguat impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
25reference materials
1isotope-labelled
COAHPLC · NMR · MS on request
![1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile chemical structure](/media/structures/CSUUGTRFBZTTQW-UHFFFAOYSA-N.svg)
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
- CAS
- 256376-65-5
- Formula
- C14H9FN4
- MW
- 252.25 g/mol
VQ-033556
![1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide chemical structure](/media/structures/GWDSAMDSGSEPRH-UHFFFAOYSA-N.svg)
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide
- CAS
- 256376-62-2
- Formula
- C14H11FN4O
- MW
- 270.26 g/mol
VQ-033555
![1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride chemical structure](/media/structures/DQASIYVADJWVLY-UHFFFAOYSA-N.svg)
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride
- CAS
- 256499-19-1
- Formula
- C14H13ClFN5
- MW
- 305.74 g/mol
VQ-041921
![1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester chemical structure](/media/structures/KZVKXYSMYGMEPB-UHFFFAOYSA-N.svg)
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester
- CAS
- 256376-59-7
- Formula
- C16H14FN3O2
- MW
- 299.3 g/mol
VQ-033560
![6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-7H-purin-8(9H)-one chemical structure](/media/structures/CAIIQYLLHWTWLI-UHFFFAOYSA-N.svg)
6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-7H-purin-8(9H)-one
- CAS
- 1361569-18-7
- Formula
- C19H15FN8O
- MW
- 390.4 g/mol
VQ-027827
![6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7,9-dihydro-8H-purin-8-one chemical structure](/media/structures/YVNXUGWVLDZUEP-UHFFFAOYSA-N.svg)
6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7,9-dihydro-8H-purin-8-one
- CAS
- 1361569-23-4
- Formula
- C20H17FN8O
- MW
- 404.4 g/mol
VQ-033554
![6-Amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one chemical structure](/media/structures/XCHOOCNZQCRKNW-UHFFFAOYSA-N.svg)
6-Amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one
- CAS
- 1361569-10-9
- Formula
- C18H13FN8O
- MW
- 376.3 g/mol
VQ-027826
![Methyl (4,6-diamino-2-(1-benzyl-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate](/media/pack/methyl-46-diamino-2-1-benzyl-5-fluoro-1h-pyrazolo34-bpyridin-3-ylpyrimidin-5-ylcarbamate.svg?v=3)
Methyl (4,6-diamino-2-(1-benzyl-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate
- CAS
- 3052969-91-9
- Formula
- C19H17FN8O2
- MW
- 408.39 g/mol
VQ-041922
![Methyl 1-[(2-Fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboximidate chemical structure](/media/structures/WSKGRWHECMNHBT-UHFFFAOYSA-N.svg)
Methyl 1-[(2-Fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboximidate
- CAS
- 304874-06-4
- Formula
- C15H13FN4O
- MW
- 284.29 g/mol
VQ-027829
FAQs — Riociguat impurities
Which Riociguat impurities do you supply?
We list 25 Riociguat-related reference materials, including process impurities, degradation products, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Riociguat impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Riociguat impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
Request Riociguat impurity standards
We reply within one business day with price, pack options, lead time and documentation.