Rivaroxaban impurity

Name: Rivaroxaban impurity
Brand: Vaqora Chemicals
SKU: VQ-023393

About Rivaroxaban impurity

Vaqora Chemicals supplies Rivaroxaban impurity, a metabolite or degradation product of Rivaroxaban registered under CAS number 148857-42-5. With the molecular formula C11H10ClNO3, it has a molar mass of 239.65 g/mol. The IUPAC name is 2-[(2S)-3-chloro-2-hydroxypropyl]isoindole-1,3-dione. Alternative names: Rivaroxaban Impurity 49 and Rivaroxaban Impurity 1.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Rivaroxaban, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Rivaroxaban impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Rivaroxaban impurity
Catalogue No.	VQ-023393
CAS Number	148857-42-5
IUPAC name	2-[(2S)-3-chloro-2-hydroxypropyl]isoindole-1,3-dione
Molecular formula	C₁₁H₁₀ClNO₃
Molecular weight	239.65 g/mol
Exact mass	239.0349
Grade	Reference Standard
HSN code	38229090
InChIKey	KBRVYEPWGIQEOF-SSDOTTSWSA-N
SMILES	C1=CC=C2C(=C1)C(=O)N(C2=O)C[C@@H](CCl)O
PubChem CID	1070653

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	1 / 3
TPSA	57.6 Å²
Synonyms	2-[(2S)-3-chloro-2-hydroxypropyl]-2,3-dihydro-1H-isoindole-1,3-dione, 2-((2S)-3-chloro-2-hydroxypropyl)-2,3-dihydro-1H-isoindole-1,3-dione, (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione, 2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione, Rivaroxaban Impurity 49, 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-3-chloro-2-hydroxypropyl]-, Rivaroxaban Impurity 1, 1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-, (S)-, CS-M0559, (s)-1-phthalimido-3-chloro-2-propanol, (S)-1-Phthlimido-3-chloro-2-propanol, (S)-2-(3-Chloro-2-hydroxy-propyl)-isoindole-1,3-dione

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rivaroxaban impurity?

The CAS Registry Number of Rivaroxaban impurity is 148857-42-5. It is also known as 2-[(2S)-3-chloro-2-hydroxypropyl]-2,3-dihydro-1H-isoindole-1,3-dione, 2-((2S)-3-chloro-2-hydroxypropyl)-2,3-dihydro-1H-isoindole-1,3-dione, (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione.

What is the molecular formula and molecular weight of Rivaroxaban impurity?

Rivaroxaban impurity has the molecular formula C11H10ClNO3 and a molecular weight of 239.65 g/mol. Its IUPAC name is 2-[(2S)-3-chloro-2-hydroxypropyl]isoindole-1,3-dione.

What is Rivaroxaban impurity used for?

Rivaroxaban impurity is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rivaroxaban impurity can I order?

We supply Rivaroxaban impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rivaroxaban impurity?

Yes. Every lot of Rivaroxaban impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rivaroxaban impurity be shipped internationally?

Yes. Rivaroxaban impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.