Ruxolitinib Pyrazole Deazapurine Pyrimidine I… 941685-27-4

Name: Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity
Brand: Vaqora Chemicals
SKU: VQ-005850

About Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity

Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity is an impurity of Ruxolitinib carrying the CAS registry number 941685-27-4. With the molecular formula C15H21N5OSi, it has a molar mass of 315.45 g/mol. The IUPAC name is trimethyl-[2-[[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methoxy]ethyl]silane. Common synonyms include C15H21N5OSi.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Ruxolitinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity
Catalogue No.	VQ-005850
CAS Number	941685-27-4
IUPAC name	trimethyl-[2-[[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methoxy]ethyl]silane
Molecular formula	C₁₅H₂₁N₅OSi
Molecular weight	315.45 g/mol
Exact mass	315.1515
Grade	Reference Standard
HSN code	38229090
InChIKey	AVMLPTWVYQXRSV-UHFFFAOYSA-N
SMILES	C[Si](C)(C)CCOCN1C=CC2=C(N=CN=C21)C3=CNN=C3
PubChem CID	42631346

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 4
TPSA	68.6 Å²
Synonyms	4-(1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine, 4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine, 4-(1H-pyrazol-4-yl)-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine, 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo(2,3-d)pyrimidine, 4-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidine, 4-(1H-Pyrazol-4-yl)-7-[2-(trimethylsilyl)ethoxy]methyl-7 H-pyrrolo[2,3-d]-pyrimidine, 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine, 4-(4-Pyrazolyl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine, 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl-7H-pyrrolo[2,3-d]pyrimidine, 4-(7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole, C15H21N5OSi, 4-(7-[[2-(Trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity?

The CAS Registry Number of Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity is 941685-27-4. It is also known as 4-(1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine, 4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine, 4-(1H-pyrazol-4-yl)-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine.

What is the molecular formula and molecular weight of Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity?

Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity has the molecular formula C15H21N5OSi and a molecular weight of 315.45 g/mol. Its IUPAC name is trimethyl-[2-[[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methoxy]ethyl]silane.

What is Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity used for?

Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity can I order?

We supply Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity?

Yes. Every lot of Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity be shipped internationally?

Yes. Ruxolitinib Pyrazole Deazapurine Pyrimidine Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.