((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methyl… 2603450-03-7

Name: ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid
Brand: Vaqora Chemicals
SKU: VQ-042714

About ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid

Vaqora Chemicals supplies ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid, an impurity of Trofinetide registered under CAS number 2603450-03-7. Its molecular formula is C21H27N3O8 and its molecular weight is 449.5 g/mol. The IUPAC name is (2S)-2-[[(2S)-2-methyl-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carbonyl]amino]pentanedioic acid. Alternative names: Cbz-Gly-aMePro-Glu-OH.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Trofinetide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trofinetide

View every impurity, metabolite and intermediate we list for Trofinetide.

Trofinetide impurities

Specifications & identifiers

Chemical identifiers
Product name	((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid
Catalogue No.	VQ-042714
CAS Number	2603450-03-7
IUPAC name	(2S)-2-[[(2S)-2-methyl-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carbonyl]amino]pentanedioic acid
Molecular formula	C₂₁H₂₇N₃O₈
Molecular weight	449.5 g/mol
Exact mass	449.1798
Grade	Reference Standard
HSN code	38229090
InChIKey	ROQWANBWHXDDNM-BTYIYWSLSA-N
SMILES	C[C@]1(CCCN1C(=O)CNC(=O)OCC2=CC=CC=C2)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	67171960

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	4 / 8
TPSA	162 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid?

The CAS Registry Number of ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid is 2603450-03-7. It is also known as Cbz-Gly-aMePro-Glu-OH.

What is the molecular formula and molecular weight of ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid?

((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid has the molecular formula C21H27N3O8 and a molecular weight of 449.5 g/mol. Its IUPAC name is (2S)-2-[[(2S)-2-methyl-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carbonyl]amino]pentanedioic acid.

What is ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid used for?

((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid is supplied as a characterised reference material related to Trofinetide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid can I order?

We supply ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid?

Yes. Every lot of ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid be shipped internationally?

Yes. We export ((S)-1-(((Benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.