(S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidi… 103336-06-7

Name: (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-040401

About (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid

Vaqora Chemicals supplies (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid, an impurity of Trofinetide registered under CAS number 103336-06-7. Its molecular formula is C11H19NO4 and its molecular weight is 229.27 g/mol. Systematically, it is named (2S)-2-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid. Common synonyms include N-Boc-2-Methyl-L-Proline and 1-Boc-2-methyl-L-proline.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Trofinetide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trofinetide

View every impurity, metabolite and intermediate we list for Trofinetide.

Trofinetide impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid
Catalogue No.	VQ-040401
CAS Number	103336-06-7
IUPAC name	(2S)-2-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
Molecular formula	C₁₁H₁₉NO₄
Molecular weight	229.27 g/mol
Exact mass	229.1314
Grade	Reference Standard
HSN code	38229090
InChIKey	YQXRKJHVAUKXRN-NSHDSACASA-N
SMILES	C[C@]1(CCCN1C(=O)OC(C)(C)C)C(=O)O
PubChem CID	11206950

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 4
TPSA	66.8 Å²
Synonyms	N-Boc-2-Methyl-L-Proline, 1-Boc-2-methyl-L-proline, (2S)-1-[(tert-butoxy)carbonyl]-2-methylpyrrolidine-2-carboxylic acid, 1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester,(2S)-, (S)-2-Methylpyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, (2S)-1-tert-butoxycarbonyl-2-methyl-pyrrolidine-2-carboxylic acid, (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, Boc-alpha-Me-Pro-OH, 1-(tert-butoxycarbonyl)-2-methylproline, Boc-, A-Me-Pro-OH, Boc-alpha-Methyl-L-Proline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid?

The CAS Registry Number of (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid is 103336-06-7. It is also known as N-Boc-2-Methyl-L-Proline, 1-Boc-2-methyl-L-proline, (2S)-1-[(tert-butoxy)carbonyl]-2-methylpyrrolidine-2-carboxylic acid.

What is the molecular formula and molecular weight of (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid?

(S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid has the molecular formula C11H19NO4 and a molecular weight of 229.27 g/mol. Its IUPAC name is (2S)-2-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid.

What is (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid used for?

(S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid is supplied as a characterised reference material related to Trofinetide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid can I order?

We supply (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid?

Yes. Every lot of (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid be shipped internationally?

Yes. (S)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.