![(S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide (CAS 2379402-85-2) chemical structure](/media/structures/KDNFAOHHDGPOSG-AWEZNQCLSA-N.svg)
VAQORASynonyms: Bortezomib Hydroxy ketone analog
(S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide (CAS 2379402-85-2) – Bortezomib impurity standard. COA included.
Listed under CAS 2379402-85-2, (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide is a metabolite or degradation product of Bortezomib available from Vaqora Chemicals. The compound has the formula C19H22N4O4, corresponding to a molecular weight of 370.4 g/mol. Its systematic (IUPAC) name is N-[(2S)-1-[(3-hydroxy-3-methylbutanoyl)amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide. It is also known as Bortezomib Hydroxy ketone analog.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.
It is used in metabolite identification, stability-indicating method development and impurity profiling of Bortezomib, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.
We offer (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.
View every impurity, metabolite and intermediate we list for Bortezomib.
Bortezomib impurities| Product name | (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide |
|---|---|
| Catalogue No. | VQ-024616 |
| CAS Number | 2379402-85-2 |
| IUPAC name | N-[(2S)-1-[(3-hydroxy-3-methylbutanoyl)amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide |
| Molecular formula | C19H22N4O4 |
| Molecular weight | 370.4 g/mol |
| Exact mass | 370.1641 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | KDNFAOHHDGPOSG-AWEZNQCLSA-N |
| SMILES | CC(C)(CC(=O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)O |
| PubChem CID | 125279266 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.4 |
| H-bond donors / acceptors | 3 / 6 |
| TPSA | 121 Ų |
The CAS Registry Number of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide is 2379402-85-2. It is also known as Bortezomib Hydroxy ketone analog.
(S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide has the molecular formula C19H22N4O4 and a molecular weight of 370.4 g/mol. Its IUPAC name is N-[(2S)-1-[(3-hydroxy-3-methylbutanoyl)amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide.
(S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
We supply (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Yes. Every lot of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Yes. We export (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
We reply within one business day with price, pack options, lead time and documentation.
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