(S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylp… 862894-96-0

Name: (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Brand: Vaqora Chemicals
SKU: VQ-021861

About (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Vaqora Chemicals supplies (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide, an impurity of Bortezomib registered under CAS number 862894-96-0. The compound has the formula C19H22N4O3, corresponding to a molecular weight of 354.4 g/mol. The IUPAC name is N-[(2S)-1-(3-methylbutanoylamino)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide. It is also known as 3-Hydroxy-1-oxo-1-des(boric acid)-bortezomib.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Bortezomib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.	VQ-021861
CAS Number	862894-96-0
IUPAC name	N-[(2S)-1-(3-methylbutanoylamino)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Molecular formula	C₁₉H₂₂N₄O₃
Molecular weight	354.4 g/mol
Exact mass	354.1692
Grade	Reference Standard
HSN code	38229090
InChIKey	WREPYMVPDVCLPX-HNNXBMFYSA-N
SMILES	CC(C)CC(=O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2
PubChem CID	71607432

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 5
TPSA	101 Å²
Synonyms	N-[(1S)-1-Benzyl-2-(3-methylbutanoylamino)-2-oxoethyl]pyrazine-2-carboxamide, (2S)-N-(3-methylbutanoyl)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamide, 3-Hydroxy-1-oxo-1-des(boric acid)-bortezomib, N-(3-Methylbutanoyl)-Nalpha-(pyrazine-2-carbonyl)-L-phenylalaninamide, N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide, (S)-, N-[(1S)-2-[(3-Methyl-1-oxobutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide, Pyrazinecarboxamide, N-[(1S)-2-[(3-methyl-1-oxobutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide?

The CAS Registry Number of (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide is 862894-96-0. It is also known as N-[(1S)-1-Benzyl-2-(3-methylbutanoylamino)-2-oxoethyl]pyrazine-2-carboxamide, (2S)-N-(3-methylbutanoyl)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamide, 3-Hydroxy-1-oxo-1-des(boric acid)-bortezomib.

What is the molecular formula and molecular weight of (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide?

(S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide has the molecular formula C19H22N4O3 and a molecular weight of 354.4 g/mol. Its IUPAC name is N-[(2S)-1-(3-methylbutanoylamino)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide.

What is (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide used for?

(S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide can I order?

We supply (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide?

Yes. Every lot of (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide be shipped internationally?

Yes. We export (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.