Sacubitril Amino Acid Impurity

Name: Sacubitril Amino Acid Impurity
Brand: Vaqora Chemicals
SKU: VQ-005854

About Sacubitril Amino Acid Impurity

Vaqora Chemicals supplies Sacubitril Amino Acid Impurity, an impurity of Sacubitril registered under CAS number 1038924-71-8. With the molecular formula C18H22ClNO2, it has a molar mass of 319.8 g/mol. Systematically, it is named (2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid. Hydrochloride. It is also known as Sacubitril Impurity 11 (Hydrochloride) or Sacubitril impurity 11.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Sacubitril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril Amino Acid Impurity
Catalogue No.	VQ-005854
CAS Number	1038924-71-8
Other CAS	1039307-95-3
IUPAC name	(2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid;hydrochloride
Molecular formula	C₁₈H₂₂ClNO₂
Molecular weight	319.8 g/mol
Exact mass	319.1339
Grade	Reference Standard
HSN code	38229090
InChIKey	YDSBMWIJMJQNKE-YNDBEVAQSA-N
SMILES	C[C@H](C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)N)C(=O)O.Cl
PubChem CID	25017084

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 3
TPSA	63.3 Å²
Synonyms	Sacubitril Impurity 11 (Hydrochloride), (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoic acid hydrochloride, (αR,γS)-γ-Amino-α-methyl[1,1′-biphenyl]-4-pentanoic acid hydrochloride, (2R,4S)-4-Amino-5-([1,1′-biphenyl]-4-yl)-2-methyl-pentanoic acid hydrochloride, (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid hydrochloride, (2R,4S)-5-([1,1′-Biphenyl]-4-yl)-4-amino-2-methylpentanoic acid hydrochloride, Sacubitril impurity 11, (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride, Sacubitril RC 12 (HCl), LCZ-696 Impurity 2 HCl, (2R, 4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride, (2R,4S)-5-(4-Biphenylyl)-4-amino-2-methylpentanoic Acid Hydrochloride

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril Amino Acid Impurity?

The CAS Registry Number of Sacubitril Amino Acid Impurity is 1038924-71-8. It is also known as Sacubitril Impurity 11 (Hydrochloride), (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoic acid hydrochloride, (αR,γS)-γ-Amino-α-methyl[1,1′-biphenyl]-4-pentanoic acid hydrochloride.

What is the molecular formula and molecular weight of Sacubitril Amino Acid Impurity?

Sacubitril Amino Acid Impurity has the molecular formula C18H22ClNO2 and a molecular weight of 319.8 g/mol.

What is Sacubitril Amino Acid Impurity used for?

Sacubitril Amino Acid Impurity is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril Amino Acid Impurity can I order?

We supply Sacubitril Amino Acid Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril Amino Acid Impurity?

Yes. Every lot of Sacubitril Amino Acid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril Amino Acid Impurity be shipped internationally?

Yes. We export Sacubitril Amino Acid Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.