Scopine

Name: Scopine
Brand: Vaqora Chemicals
SKU: VQ-032842

About Scopine

Vaqora Chemicals supplies Scopine, an impurity of Tiotropium registered under CAS number 498-45-3. Formula C8H13NO2, molecular weight 155.19 g/mol. Systematically, it is named (1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol. Common synonyms include 6,7-Epoxytropine and Scopin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Tiotropium to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tiotropium

View every impurity, metabolite and intermediate we list for Tiotropium.

Tiotropium impurities

Specifications & identifiers

Chemical identifiers
Product name	Scopine
Catalogue No.	VQ-032842
CAS Number	498-45-3
IUPAC name	(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol
Molecular formula	C₈H₁₃NO₂
Molecular weight	155.19 g/mol
Exact mass	155.0946
Grade	Reference Standard
HSN code	38229090
InChIKey	FIMXSEMBHGTNKT-UPGAHCIJSA-N
SMILES	CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)O
PubChem CID	1274465

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	1 / 3
TPSA	36 Å²
Synonyms	(1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo(3.3.1.02,4)nonan-7-ol, 6,7-Epoxytropine, (1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, Scopin, rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, Isoscopine, (1R,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, Scopanol, (1R,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0,2,4]nonan-7-ol, (1R,2R,4S,5S,7r)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-7-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Scopine?

The CAS Registry Number of Scopine is 498-45-3. It is also known as (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo(3.3.1.02,4)nonan-7-ol, 6,7-Epoxytropine.

What is the molecular formula and molecular weight of Scopine?

Scopine has the molecular formula C8H13NO2 and a molecular weight of 155.19 g/mol. Its IUPAC name is (1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol.

What is Scopine used for?

Scopine is supplied as a characterised reference material related to Tiotropium. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Scopine can I order?

We supply Scopine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Scopine?

Yes. Every lot of Scopine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Scopine be shipped internationally?

Yes. We export Scopine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.