Scopoline

Name: Scopoline
Brand: Vaqora Chemicals
SKU: VQ-033791

About Scopoline

Scopoline (CAS 487-27-4) is a high-purity reference standard of Tiotropium offered by Vaqora Chemicals. With the molecular formula C8H13NO2, it has a molar mass of 155.19 g/mol. Its systematic (IUPAC) name is (1S,3S,4S,5S,7R)-6-methyl-2-oxa-6-azatricyclo[3.3.1.03,7]nonan-4-ol. Common synonyms include Oscin and Oscine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Tiotropium, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Scopoline is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tiotropium

View every impurity, metabolite and intermediate we list for Tiotropium.

Tiotropium impurities

Specifications & identifiers

Chemical identifiers
Product name	Scopoline
Catalogue No.	VQ-033791
CAS Number	487-27-4
IUPAC name	(1S,3S,4S,5S,7R)-6-methyl-2-oxa-6-azatricyclo[3.3.1.03,7]nonan-4-ol
Molecular formula	C₈H₁₃NO₂
Molecular weight	155.19 g/mol
Exact mass	155.0946
Grade	Reference Standard
HSN code	38229090
InChIKey	MEGPURSNXMUDAE-RLMOJYMMSA-N
SMILES	CN1[C@H]2C[C@H]3C[C@@H]1[C@@H]([C@H]2O)O3
PubChem CID	25084503

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	1 / 3
TPSA	32.7 Å²
Synonyms	Oscin, Oscine, 1betaH,5betaH-Tropan-6alpha-ol, 3beta,7beta-epoxy-, (1S,3S,4S,5S,7R)-6-methyl-2-oxa-6-azatricyclo(3.3.1.03,7)nonan-4-ol, 2,5-Methano-2H-furo[3,2-b]pyrrol-6-ol, hexahydro-4-methyl-, (2R,3aS,5R,6R,6aR)-rel-, 1betaH,5betaH-Tropan-6alpha-ol, 3beta,7beta-epoxy-(8CI)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Scopoline?

The CAS Registry Number of Scopoline is 487-27-4. It is also known as Oscin, Oscine, 1betaH,5betaH-Tropan-6alpha-ol, 3beta,7beta-epoxy-.

What is the molecular formula and molecular weight of Scopoline?

Scopoline has the molecular formula C8H13NO2 and a molecular weight of 155.19 g/mol. Its IUPAC name is (1S,3S,4S,5S,7R)-6-methyl-2-oxa-6-azatricyclo[3.3.1.03,7]nonan-4-ol.

What is Scopoline used for?

Scopoline is supplied as a characterised reference material related to Tiotropium. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Scopoline can I order?

We supply Scopoline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Scopoline?

Yes. Every lot of Scopoline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Scopoline be shipped internationally?

Yes. Scopoline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.