Sertraline EP Impurity B (Hydrochloride)

Name: Sertraline EP Impurity B (Hydrochloride)
Brand: Vaqora Chemicals
SKU: VQ-006686

About Sertraline EP Impurity B (Hydrochloride)

Sertraline EP Impurity B (Hydrochloride) is a pharmacopeial impurity of Sertraline carrying the CAS registry number 52758-05-1 with a typical assay of 99.57%. Formula C17H20ClN, molecular weight 273.8 g/mol. The IUPAC name is (1S,4S)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine. Hydrochloride. Alternative names: rac-cis-3,4-Deschlorosertraline and Tametraline hydrochloride, cis-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Sertraline to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sertraline EP Impurity B (Hydrochloride) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Sertraline

View every impurity, metabolite and intermediate we list for Sertraline.

Sertraline impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sertraline EP Impurity B (Hydrochloride)
Catalogue No.	VQ-006686
CAS Number	52758-05-1
Other CAS	52758-03-9
IUPAC name	(1S,4S)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride
Molecular formula	C₁₇H₂₀ClN
Molecular weight	273.8 g/mol
Exact mass	273.1284
Grade	Reference Standard
Purity / assay	99.57%
HSN code	38229090
InChIKey	XTSOELQVDLSJFM-RVXRQPKJSA-N
SMILES	CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC=CC=C3.Cl
PubChem CID	3034724

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 1
TPSA	12 Å²
Synonyms	cis-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine Hydrochloride, cis-(±)-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine Hydrochloride, (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride, rac-cis-3,4-Deschlorosertraline, 1-Naphthylamine, 1,2,3,4-tetrahydro-N-methyl-4-phenyl-, hydrochloride, (Z)-, cis-1,2,3,4-Tetrahydro-1-amino-N-methyl-4-phenylnaphthalene hydrochloride, cis-N-Methyl-4-phenyl-1,2,3,4-tetrahydro-1-naphthylamine hydrochloride, (1S,4S)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride, Tametraline hydrochloride, cis-, 52758-05-1(HCl salt), Tametraline hydrochloride, 1S-cis-, rac-cis-3,4-Deschlorosertraline hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sertraline EP Impurity B (Hydrochloride)?

The CAS Registry Number of Sertraline EP Impurity B (Hydrochloride) is 52758-05-1. It is also known as cis-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine Hydrochloride, cis-(±)-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine Hydrochloride, (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride.

What is the molecular formula and molecular weight of Sertraline EP Impurity B (Hydrochloride)?

Sertraline EP Impurity B (Hydrochloride) has the molecular formula C17H20ClN and a molecular weight of 273.8 g/mol.

What is Sertraline EP Impurity B (Hydrochloride) used for?

Sertraline EP Impurity B (Hydrochloride) is supplied as a characterised reference material related to Sertraline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sertraline EP Impurity B (Hydrochloride) can I order?

We supply Sertraline EP Impurity B (Hydrochloride) in Reference Standard (99.57%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sertraline EP Impurity B (Hydrochloride)?

Yes. Every lot of Sertraline EP Impurity B (Hydrochloride) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sertraline EP Impurity B (Hydrochloride) be shipped internationally?

Yes. Sertraline EP Impurity B (Hydrochloride) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.