Sitagliptin Dioxo Impurity
Synonyms: 2,2-Dimethyl-5-[[1-hydroxy-2-( 2,4,5-trifluorophenyl)ethylidene]-1,3-dioxane-4,6-dione · 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione · 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione · Sitagliptin Impurity 52
Sitagliptin Dioxo Impurity (CAS 764667-64-3) – Sitagliptin impurity standard. C14H11F3O5, MW 316.23. Request a quote: COA, bulk packs and worldwide export.
About Sitagliptin Dioxo Impurity
Sitagliptin Dioxo Impurity (CAS 764667-64-3) is an impurity of Sitagliptin offered by Vaqora Chemicals. The compound has the formula C14H11F3O5, corresponding to a molecular weight of 316.23 g/mol. Its systematic (IUPAC) name is 5-[1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione. Alternative names: Sitagliptin Impurity 52.
It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.
Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Sitagliptin.
Sitagliptin impuritiesSpecifications & identifiers
| Product name | Sitagliptin Dioxo Impurity |
|---|---|
| Catalogue No. | VQ-005920 |
| CAS Number | 764667-64-3 |
| Other CAS | 1253055-91-2, 1253056-21-1 |
| IUPAC name | 5-[1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione |
| Molecular formula | C14H11F3O5 |
| Molecular weight | 316.23 g/mol |
| Exact mass | 316.0559 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | COUGIGFQGFTRPG-UHFFFAOYSA-N |
| SMILES | CC1(OC(=O)C(=C(CC2=CC(=C(C=C2F)F)F)O)C(=O)O1)C |
| PubChem CID | 54711477 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3.3 |
| H-bond donors / acceptors | 1 / 8 |
| TPSA | 72.8 Ų |
| Synonyms | 2,2-Dimethyl-5-[[1-hydroxy-2-( 2,4,5-trifluorophenyl)ethylidene]-1,3-dioxane-4,6-dione, 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione, 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione, Sitagliptin Impurity 52, 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimet, 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)-ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione |
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Frequently asked questions
What is the CAS number of Sitagliptin Dioxo Impurity?
The CAS Registry Number of Sitagliptin Dioxo Impurity is 764667-64-3. It is also known as 2,2-Dimethyl-5-[[1-hydroxy-2-( 2,4,5-trifluorophenyl)ethylidene]-1,3-dioxane-4,6-dione, 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione, 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione.
What is the molecular formula and molecular weight of Sitagliptin Dioxo Impurity?
Sitagliptin Dioxo Impurity has the molecular formula C14H11F3O5 and a molecular weight of 316.23 g/mol. Its IUPAC name is 5-[1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione.
What is Sitagliptin Dioxo Impurity used for?
Sitagliptin Dioxo Impurity is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Sitagliptin Dioxo Impurity can I order?
We supply Sitagliptin Dioxo Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Sitagliptin Dioxo Impurity?
Yes. Every lot of Sitagliptin Dioxo Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Sitagliptin Dioxo Impurity be shipped internationally?
Yes. We export Sitagliptin Dioxo Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about Sitagliptin Dioxo Impurity
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