Sitagliptin FP Impurity D

Name: Sitagliptin FP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-005926

About Sitagliptin FP Impurity D

Sitagliptin FP Impurity D is an impurity of Sitagliptin carrying the CAS registry number 1253056-18-6 with a typical assay of 97.6%. With the molecular formula C16H12F6N4O, it has a molar mass of 390.28 g/mol. It is also known as 3-Desamino-2,3-dehydro Sitagliptin or Sitagliptin Deamino Impurity 1.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Sitagliptin FP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin FP Impurity D
Catalogue No.	VQ-005926
CAS Number	1253056-18-6
IUPAC name	(E)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one
Molecular formula	C₁₆H₁₂F₆N₄O
Molecular weight	390.28 g/mol
Exact mass	390.0915
Grade	Reference Standard
Purity / assay	97.6%
HSN code	38229090
InChIKey	QSSHJJFVCWMIKH-HNQUOIGGSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)/C=C/CC3=CC(=C(C=C3F)F)F
PubChem CID	49783992

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 9
TPSA	51 Å²
Synonyms	3-Desamino-2,3-dehydro Sitagliptin, Sitagliptin Deamino Impurity 1, Sitagliptin Phenylcrotonyl Analog, Sitagliptin impurity D, Sitagliptin Impurity FP-D, Sitagliptin Phenyl Crotonyl Analog, Sitagliptin USP Phenylcrotonyl Analog, (E)-1-(3-(trifluoromethyl)-5,6-dihydro

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin FP Impurity D?

The CAS Registry Number of Sitagliptin FP Impurity D is 1253056-18-6. It is also known as 3-Desamino-2,3-dehydro Sitagliptin, Sitagliptin Deamino Impurity 1, Sitagliptin Phenylcrotonyl Analog.

What is the molecular formula and molecular weight of Sitagliptin FP Impurity D?

Sitagliptin FP Impurity D has the molecular formula C16H12F6N4O and a molecular weight of 390.28 g/mol. Its IUPAC name is (E)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one.

What is Sitagliptin FP Impurity D used for?

Sitagliptin FP Impurity D is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin FP Impurity D can I order?

We supply Sitagliptin FP Impurity D in Reference Standard (97.6%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin FP Impurity D?

Yes. Every lot of Sitagliptin FP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin FP Impurity D be shipped internationally?

Yes. We export Sitagliptin FP Impurity D worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.