Sitagliptin ethyl ester impurity

Name: Sitagliptin ethyl ester impurity
Brand: Vaqora Chemicals
SKU: VQ-028062

About Sitagliptin ethyl ester impurity

Sitagliptin ethyl ester impurity is an impurity of Sitagliptin carrying the CAS registry number 1151240-91-3. The compound has the formula C12H14F3NO2, corresponding to a molecular weight of 261.24 g/mol. Systematically, it is named ethyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Sitagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sitagliptin ethyl ester impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin ethyl ester impurity
Catalogue No.	VQ-028062
CAS Number	1151240-91-3
IUPAC name	ethyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate
Molecular formula	C₁₂H₁₄F₃NO₂
Molecular weight	261.24 g/mol
Exact mass	261.0977
Grade	Reference Standard
HSN code	38229090
InChIKey	SCAQGFRAYMMTNM-MRVPVSSYSA-N
SMILES	CCOC(=O)C[C@@H](CC1=CC(=C(C=C1F)F)F)N
PubChem CID	67105981

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 6
TPSA	52.3 Å²
Synonyms	(R)-Ethyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate (Sitagliptin Impuruity), Benzenebutanoic acid, beta-amino-2,4,5-trifluoro-, ethyl ester, (betaR)-, (R)-Ethyl 2,4,5-trifluoro-b-homophenylalaninateHCl, (R)-Ethyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate, Ethyl (betaR)-beta-amino-2,4,5-trifluorobenzenebutanoate, Ethyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate, (R)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin ethyl ester impurity?

The CAS Registry Number of Sitagliptin ethyl ester impurity is 1151240-91-3. It is also known as (R)-Ethyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate (Sitagliptin Impuruity), Benzenebutanoic acid, beta-amino-2,4,5-trifluoro-, ethyl ester, (betaR)-, (R)-Ethyl 2,4,5-trifluoro-b-homophenylalaninateHCl.

What is the molecular formula and molecular weight of Sitagliptin ethyl ester impurity?

Sitagliptin ethyl ester impurity has the molecular formula C12H14F3NO2 and a molecular weight of 261.24 g/mol. Its IUPAC name is ethyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate.

What is Sitagliptin ethyl ester impurity used for?

Sitagliptin ethyl ester impurity is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin ethyl ester impurity can I order?

We supply Sitagliptin ethyl ester impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin ethyl ester impurity?

Yes. Every lot of Sitagliptin ethyl ester impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin ethyl ester impurity be shipped internationally?

Yes. Sitagliptin ethyl ester impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.