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VAQORASitagliptin FP Impurity E (Freebase)
Synonyms: (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid · Sitagliptin Acid · (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic acid · Sitagliptin FP Impurity E
CAS No.936630-57-8
FormulaC10H10F3NO2
Mol. weight233.19
Catalogue No.VQ-005927
PurityReference Standard
HSN38229090
Sitagliptin FP Impurity E (Freebase) (CAS 936630-57-8) – Sitagliptin impurity standard. C10H10F3NO2, MW 233.19. Vaqora Chemicals: COA, global shipping.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About Sitagliptin FP Impurity E (Freebase)
Sitagliptin FP Impurity E (Freebase) is an impurity of Sitagliptin carrying the CAS registry number 936630-57-8. With the molecular formula C10H10F3NO2, it has a molar mass of 233.19 g/mol. The IUPAC name is (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid. Common synonyms include Sitagliptin Acid and Sitagliptin FP Impurity E.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.
Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sitagliptin FP Impurity E (Freebase) is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
Related to Sitagliptin
View every impurity, metabolite and intermediate we list for Sitagliptin.
Sitagliptin impuritiesSpecifications & identifiers
| Product name | Sitagliptin FP Impurity E (Freebase) |
|---|---|
| Catalogue No. | VQ-005927 |
| CAS Number | 936630-57-8 |
| Other CAS | 1204818-19-8 |
| IUPAC name | (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid |
| Molecular formula | C10H10F3NO2 |
| Molecular weight | 233.19 g/mol |
| Exact mass | 233.0664 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | KEFQQJVYCWLKPL-ZCFIWIBFSA-N |
| SMILES | C1=C(C(=CC(=C1F)F)F)C[C@H](CC(=O)O)N |
| PubChem CID | 7146283 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | -1.2 |
| H-bond donors / acceptors | 2 / 6 |
| TPSA | 63.3 Ų |
| Synonyms | (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid, Sitagliptin Acid, (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic acid, Sitagliptin FP Impurity E, (3r)-amino-4-(2,4,5-trifluorophenyl)butanoic acid, (3R)-3-azaniumyl-4-(2,4,5-trifluorophenyl)butanoate, Sitagliptin Impurity 33, (r)-3-amino-4-(2,4,5-trifluorophenyl)butanoicacid, Benzenebutanoic acid, beta-amino-2,4,5-trifluoro-, 3-(R)-amino-4-(2,4,5-trifluorophenyl)butanoic acid, Benzenebutanoic acid, beta-amino-2,4,5-trifluoro-, (betaR)-, benzenebutanoic acid, .beta.-amino-2,4,5-trifluoro-, (.beta.r)- |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH319Causes serious eye irritationH335May cause respiratory irritation
Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Sitagliptin FP Impurity E (Freebase)?
The CAS Registry Number of Sitagliptin FP Impurity E (Freebase) is 936630-57-8. It is also known as (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid, Sitagliptin Acid, (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic acid.
What is the molecular formula and molecular weight of Sitagliptin FP Impurity E (Freebase)?
Sitagliptin FP Impurity E (Freebase) has the molecular formula C10H10F3NO2 and a molecular weight of 233.19 g/mol. Its IUPAC name is (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid.
What is Sitagliptin FP Impurity E (Freebase) used for?
Sitagliptin FP Impurity E (Freebase) is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Sitagliptin FP Impurity E (Freebase) can I order?
We supply Sitagliptin FP Impurity E (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Sitagliptin FP Impurity E (Freebase)?
Yes. Every lot of Sitagliptin FP Impurity E (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Sitagliptin FP Impurity E (Freebase) be shipped internationally?
Yes. Sitagliptin FP Impurity E (Freebase) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Sitagliptin FP Impurity E (Freebase)
We reply within one business day with price, pack options, lead time and documentation.
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